Metallothionein modulation in relation to cadmium
bioaccumulation and age-dependent sensitivity of Chironomus
riparius larvae

J 2016

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK et. al.

Základní údaje

Originální název

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

Autoři

TOUŠOVÁ, Zuzana (203 Česká republika, domácí), Jan KUTA (203 Česká republika, domácí), David HYNEK (203 Česká republika), Vojtěch ADAM (203 Česká republika), René KIZEK (203 Česká republika), Luděk BLÁHA (203 Česká republika, domácí) a Klára HILSCHEROVÁ (203 Česká republika, garant, domácí)

Vydání

Environmental Science and Pollution Research, Landsberg, Germany, Ecomed, 2016, 0944-1344

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30304 Public and environmental health

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.741

Kód RIV

RIV/00216224:14310/16:00093481

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1007/s11356-016-6362-5

UT WoS

000377021500018

Klíčová slova anglicky

Chironomus; Artificial sediment; Cadmium; Bioaccumulation; Metallothionein

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 3. 2017 12:23, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

The goal of this study was to contribute to understanding of the mechanisms behind sensitivity differences between early and late instar larvae of Chironomus riparius and to address the influence of the differences in standard testing approaches on the toxicity evaluation. A 10-day contact sediment toxicity test was carried out to assess sensitivity to cadmium exposure in relation to different age and laboratory culture line origin of test organisms. Chironomid larvae of early (OECD 218 method) and late instar (US-EPA600/R-99/064 method) differed substantially in sensitivity of traditional endpoints (OECD: LOEC 50 and 10 mu g Cd/g dry weight (dw); US-EPA: LOEC > 1000 and 100 mu g Cd/g dw for survival and growth, respectively). Bioaccumulated cadmium and metallothioneins (MTs) concentrations were analyzed to investigate the role of MTs in reduced sensitivity to cadmium in late instar larvae. Metallothioneins were induced after treatment to greater Cd concentrations, but their levels in relation to cadmium body burdens did not fully explain low sensitivity of late instars to cadmium, which indicates some other effective way of detoxification in late instars. This study brings new information related to the role of MTs in age-dependent toxicant sensitivity and discusses the implications of divergence in data generated by chironomid sediment toxicity tests by standardized methods using different instars.

Návaznosti

LM2011028, projekt VaV

Název: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX Národní infrastruktura pro výzkum toxických látek v prostředí

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK, Luděk BLÁHA a Klára HILSCHEROVÁ. Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae. Environmental Science and Pollution Research. Landsberg, Germany: Ecomed, 2016, roč. 23, č. 11, s. 10504-10513. ISSN 0944-1344. Dostupné z: https://dx.doi.org/10.1007/s11356-016-6362-5.

@article{1371972,
   author = {Toušová, Zuzana and Kuta, Jan and Hynek, David and Adam, Vojtěch and Kizek, René and Bláha, Luděk and Hilscherová, Klára},
   article_location = {Landsberg, Germany},
   article_number = {11},
   doi = {http://dx.doi.org/10.1007/s11356-016-6362-5},
   keywords = {Chironomus; Artificial sediment; Cadmium; Bioaccumulation; Metallothionein},
   language = {eng},
   issn = {0944-1344},
   journal = {Environmental Science and Pollution Research},
   title = {Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae},
   url = {http://link.springer.com/article/10.1007%2Fs11356-016-6362-5},
   volume = {23},
   year = {2016}
}

TY  - JOUR
ID  - 1371972
AU  - Toušová, Zuzana - Kuta, Jan - Hynek, David - Adam, Vojtěch - Kizek, René - Bláha, Luděk - Hilscherová, Klára
PY  - 2016
TI  - Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae
JF  - Environmental Science and Pollution Research
VL  - 23
IS  - 11
SP  - 10504-10513
EP  - 10504-10513
PB  - Ecomed
SN  - 09441344
KW  - Chironomus
KW  - Artificial sediment
KW  - Cadmium
KW  - Bioaccumulation
KW  - Metallothionein
UR  - http://link.springer.com/article/10.1007%2Fs11356-016-6362-5
L2  - http://link.springer.com/article/10.1007%2Fs11356-016-6362-5
N2  - The goal of this study was to contribute to understanding of the mechanisms behind sensitivity differences between early and late instar larvae of Chironomus riparius and to address the influence of the differences in standard testing approaches on the toxicity evaluation. A 10-day contact sediment toxicity test was carried out to assess sensitivity to cadmium exposure in relation to different age and laboratory culture line origin of test organisms. Chironomid larvae of early (OECD 218 method) and late instar (US-EPA600/R-99/064 method) differed substantially in sensitivity of traditional endpoints (OECD: LOEC 50 and 10 mu g Cd/g dry weight (dw); US-EPA: LOEC > 1000 and 100 mu g Cd/g dw for survival and growth, respectively). Bioaccumulated cadmium and metallothioneins (MTs) concentrations were analyzed to investigate the role of MTs in reduced sensitivity to cadmium in late instar larvae. Metallothioneins were induced after treatment to greater Cd concentrations, but their levels in relation to cadmium body burdens did not fully explain low sensitivity of late instars to cadmium, which indicates some other effective way of detoxification in late instars. This study brings new information related to the role of MTs in age-dependent toxicant sensitivity and discusses the implications of divergence in data generated by chironomid sediment toxicity tests by standardized methods using different instars.
ER  -

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK, Luděk BLÁHA a Klára HILSCHEROVÁ. Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae. \textit{Environmental Science and Pollution Research}. Landsberg, Germany: Ecomed, 2016, roč.~23, č.~11, s.~10504-10513. ISSN~0944-1344. Dostupné z: https://dx.doi.org/10.1007/s11356-016-6362-5.

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