| DI PAOLO, Carolina, Richard OTTERMANNS, Steffen KEITER, Selim AIT-AISSA, Kerstin BLUHM, Werner BRACK, Magnus BREITHOLTZ, Sebastian BUCHINGER, Mario CARERE, Carole CHALON, Xavier COUSIN, Valeria DULIO, Beate I. ESCHER, Timo HAMERS, Klára HILSCHEROVÁ, Sergio JARQUE ORTIZ, Adam JONÁŠ, Emmanuelle MAILLOT-MARECHAL, Yves MARNEFFE, Mai Thao NGUYEN, Pascal PANDARD, Andrea SCHIFFERLI, Tobias SCHULZE, Sven SEIDENSTICKER, Thomas-Benjamin SEILER, Janet TANG, Ron VAN DER OOST, Etienne VERMEIRSSEN, Radka ZOUNKOVÁ, Nick ZWART a Henner HOLLERT. Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring. Water Research. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2016, roč. 104, November, s. 473-484. ISSN 0043-1354. Dostupné z: https://dx.doi.org/10.1016/j.watres.2016.08.018. |
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@article{1372453,
author = {Di Paolo, Carolina and Ottermanns, Richard and Keiter, Steffen and AitandAissa, Selim and Bluhm, Kerstin and Brack, Werner and Breitholtz, Magnus and Buchinger, Sebastian and Carere, Mario and Chalon, Carole and Cousin, Xavier and Dulio, Valeria and Escher, Beate I. and Hamers, Timo and Hilscherová, Klára and Jarque Ortiz, Sergio and Jonáš, Adam and MaillotandMarechal, Emmanuelle and Marneffe, Yves and Nguyen, Mai Thao and Pandard, Pascal and Schifferli, Andrea and Schulze, Tobias and Seidensticker, Sven and Seiler, ThomasandBenjamin and Tang, Janet and van der Oost, Ron and Vermeirssen, Etienne and Zounková, Radka and Zwart, Nick and Hollert, Henner},
article_location = {OXFORD},
article_number = {November},
doi = {http://dx.doi.org/10.1016/j.watres.2016.08.018},
keywords = {Triclosan; Acridine; 17 alpha-ethinylestradiol; 3-Nitrobenzanthrone; Organism-level toxicity; Mechanism-specific toxicity},
language = {eng},
issn = {0043-1354},
journal = {Water Research},
title = {Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring},
url = {http://www.sciencedirect.com/science/article/pii/S0043135416306182},
volume = {104},
year = {2016}
}
TY - JOUR
ID - 1372453
AU - Di Paolo, Carolina - Ottermanns, Richard - Keiter, Steffen - Ait-Aissa, Selim - Bluhm, Kerstin - Brack, Werner - Breitholtz, Magnus - Buchinger, Sebastian - Carere, Mario - Chalon, Carole - Cousin, Xavier - Dulio, Valeria - Escher, Beate I. - Hamers, Timo - Hilscherová, Klára - Jarque Ortiz, Sergio - Jonáš, Adam - Maillot-Marechal, Emmanuelle - Marneffe, Yves - Nguyen, Mai Thao - Pandard, Pascal - Schifferli, Andrea - Schulze, Tobias - Seidensticker, Sven - Seiler, Thomas-Benjamin - Tang, Janet - van der Oost, Ron - Vermeirssen, Etienne - Zounková, Radka - Zwart, Nick - Hollert, Henner
PY - 2016
TI - Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring
JF - Water Research
VL - 104
IS - November
SP - 473-484
EP - 473-484
PB - PERGAMON-ELSEVIER SCIENCE LTD
SN - 00431354
KW - Triclosan
KW - Acridine
KW - 17 alpha-ethinylestradiol
KW - 3-Nitrobenzanthrone
KW - Organism-level toxicity
KW - Mechanism-specific toxicity
UR - http://www.sciencedirect.com/science/article/pii/S0043135416306182
L2 - http://www.sciencedirect.com/science/article/pii/S0043135416306182
N2 - Bioassays are particularly useful tools to link the chemical and ecological assessments in water quality monitoring. Different methods cover a broad range of toxicity mechanisms in diverse organisms, and account for risks posed by non-target compounds and mixtures. There is a need to address bioassay suitability to evaluate water samples containing emerging pollutants, which are a current priority in water quality monitoring. The presented interlaboratory study (ILS) verified whether a battery of miniaturized bioassays, conducted in 11 different laboratories following their own protocols, would produce comparable results when applied to evaluate blinded samples consisting of a pristine water extract spiked with four emerging pollutants as single chemicals or mixtures, i.e. triclosan, acridine, 17 alpha-ethinylestradiol (EE2) and 3-nitrobenzanthrone (3-NBA). Assays evaluated effects on aquatic organisms from three different trophic levels and mechanism-specific effects using in vitro estrogenicity and mutagenicity assays. The test battery presented complementary sensitivity and specificity to evaluate the different blinded water extract spikes. Estrogenicity and mutagenicity assays identified with high precision the respective mechanism-specific effects of spikes even when non-specific toxicity occurred in mixture. Differences in experimental protocols, model organisms, and data analysis can be sources of variation, indicating that respective harmonized standard procedures should be followed when implementing bioassays in water monitoring. Together with other ongoing activities for the validation of a basic bioassay battery, the present study is an important step towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring.
ER -
DI PAOLO, Carolina, Richard OTTERMANNS, Steffen KEITER, Selim AIT-AISSA, Kerstin BLUHM, Werner BRACK, Magnus BREITHOLTZ, Sebastian BUCHINGER, Mario CARERE, Carole CHALON, Xavier COUSIN, Valeria DULIO, Beate I. ESCHER, Timo HAMERS, Klára HILSCHEROVÁ, Sergio JARQUE ORTIZ, Adam JONÁŠ, Emmanuelle MAILLOT-MARECHAL, Yves MARNEFFE, Mai Thao NGUYEN, Pascal PANDARD, Andrea SCHIFFERLI, Tobias SCHULZE, Sven SEIDENSTICKER, Thomas-Benjamin SEILER, Janet TANG, Ron VAN DER OOST, Etienne VERMEIRSSEN, Radka ZOUNKOVÁ, Nick ZWART a Henner HOLLERT. Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring. \textit{Water Research}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2016, roč.~104, November, s.~473-484. ISSN~0043-1354. Dostupné z: https://dx.doi.org/10.1016/j.watres.2016.08.018.
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