Buccal films as a dressing for the treatment of aphthous
lesions

J 2017

Buccal films as a dressing for the treatment of aphthous lesions

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ et. al.

Základní údaje

Originální název

Buccal films as a dressing for the treatment of aphthous lesions

Autoři

DANĚK, Zdeněk (203 Česká republika, garant, domácí), Jan GAJDZIOK (203 Česká republika), Petr DOLEŽEL (203 Česká republika), Hana LANDOVÁ (203 Česká republika), David VETCHÝ (203 Česká republika) a Jan ŠTEMBÍREK (203 Česká republika)

Vydání

Journal of Oral Pathology & Medicine, Hoboken, Wiley-Blackwell, 2017, 0904-2512

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30208 Dentistry, oral surgery and medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.237

Kód RIV

RIV/00216224:14110/17:00096270

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1111/jop.12563

UT WoS

000400193100010

Klíčová slova anglicky

aphthous lesions; mucoadhesive buccal films; oral mucosa; pain reduction; residence time

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 3. 2018 11:53, Soňa Böhmová

Anotace

V originále

Background Buccal flexible films in the form of solid, thin, mucoadhesive patches can be used as dressings separating aphthous lesions from the environment of the oral cavity, which can in turn shorten the treatment period and reduce the pain perception. Methods The clinical study was performed on 36 volunteers suffering from aphthous lesions. The first group was treated using standard means—by application of an oral gel containing cholin salicylate (Mundisal) on the aphthous lesion. The second group was treated with the same preparation; however, the lesion was covered with a mucoadhesive film following the application of the gel. The criteria for statistical evaluation were the size of lesions in relation to the length of the treatment and the subjective perception of the treatment results. Results and conclusions The application of buccal films covering aphthous lesions during the treatment significantly increased the rate of healing when compared with the standard methods of treatment. While the pain improvement was statistically significant as soon as Day 3 in the experimental group, it was only apparent on Day 5 in the control group, and the number of successfully treated patients (pain perception improving to visual analogue scale 2 or less) was at all time points higher in the experimental group than in the control group. The results imply that the use of buccal films for treatment of aphthous lesions is very promising and can lead to a significant reduction in the duration of patients’ discomfort.

Citovat

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ a Jan ŠTEMBÍREK. Buccal films as a dressing for the treatment of aphthous lesions. Journal of Oral Pathology & Medicine. Hoboken: Wiley-Blackwell, 2017, roč. 46, č. 4, s. 301-306. ISSN 0904-2512. Dostupné z: https://dx.doi.org/10.1111/jop.12563.

@article{1375079,
   author = {Daněk, Zdeněk and Gajdziok, Jan and Doležel, Petr and Landová, Hana and Vetchý, David and Štembírek, Jan},
   article_location = {Hoboken},
   article_number = {4},
   doi = {http://dx.doi.org/10.1111/jop.12563},
   keywords = {aphthous lesions; mucoadhesive buccal films; oral mucosa; pain reduction; residence time},
   language = {eng},
   issn = {0904-2512},
   journal = {Journal of Oral Pathology & Medicine},
   title = {Buccal films as a dressing for the treatment of aphthous lesions},
   volume = {46},
   year = {2017}
}

TY  - JOUR
ID  - 1375079
AU  - Daněk, Zdeněk - Gajdziok, Jan - Doležel, Petr - Landová, Hana - Vetchý, David - Štembírek, Jan
PY  - 2017
TI  - Buccal films as a dressing for the treatment of aphthous lesions
JF  - Journal of Oral Pathology & Medicine
VL  - 46
IS  - 4
SP  - 301-306
EP  - 301-306
PB  - Wiley-Blackwell
SN  - 09042512
KW  - aphthous lesions
KW  - mucoadhesive buccal films
KW  - oral mucosa
KW  - pain reduction
KW  - residence time
N2  - Background Buccal flexible films in the form of solid, thin, mucoadhesive patches can be used as dressings separating aphthous lesions from the environment of the oral cavity, which can in turn shorten the treatment period and reduce the pain perception. Methods The clinical study was performed on 36 volunteers suffering from aphthous lesions. The first group was treated using standard means—by application of an oral gel containing cholin salicylate (Mundisal) on the aphthous lesion. The second group was treated with the same preparation; however, the lesion was covered with a mucoadhesive film following the application of the gel. The criteria for statistical evaluation were the size of lesions in relation to the length of the treatment and the subjective perception of the treatment results. Results and conclusions The application of buccal films covering aphthous lesions during the treatment significantly increased the rate of healing when compared with the standard methods of treatment. While the pain improvement was statistically significant as soon as Day 3 in the experimental group, it was only apparent on Day 5 in the control group, and the number of successfully treated patients (pain perception improving to visual analogue scale 2 or less) was at all time points higher in the experimental group than in the control group. The results imply that the use of buccal films for treatment of aphthous lesions is very promising and can lead to a significant reduction in the duration of patients’ discomfort.
ER  -

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ a Jan ŠTEMBÍREK. Buccal films as a dressing for the treatment of aphthous lesions. \textit{Journal of Oral Pathology \&{} Medicine}. Hoboken: Wiley-Blackwell, 2017, roč.~46, č.~4, s.~301-306. ISSN~0904-2512. Dostupné z: https://dx.doi.org/10.1111/jop.12563.

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