Structure determination of enterovirus 71

J 2012

Structure determination of enterovirus 71

PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN, Michael G. ROSSMANN et. al.

Základní údaje

Originální název

Structure determination of enterovirus 71

Autoři

PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN a Michael G. ROSSMANN

Vydání

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, HOBOKEN, WILEY-BLACKWELL, 2012, 0907-4449

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 14.103

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1107/S0907444912025772

UT WoS

000308330000017

Klíčová slova anglicky

COMMON COLD VIRUS; DECAY-ACCELERATING FACTOR; HUMAN RHINOVIRUS-14; COXSACKIEVIRUS B3; POLIOVIRUS; CRYSTALLOGRAPHY; PICORNAVIRUS; RESOLUTION; SOFTWARE; MALAYSIA

Štítky

neMU

Změněno: 29. 3. 2017 14:31, Mgr. Eva Špillingová

Anotace

V originále

Enterovirus 71 is a picornavirus that causes hand, foot and mouth disease but may induce fatal neurological illness in infants and young children. Enterovirus 71 crystallized in a body-centered orthorhombic space group with two particles in general orientations in the crystallographic asymmetric unit. Determination of the particle orientations required that the locked rotation function excluded the twofold symmetry axes from the set of icosahedral symmetry operators. This avoided the occurrence of misleading high rotation-function values produced by the alignment of icosahedral and crystallographic twofold axes. Once the orientations and positions of the particles had been established, the structure was solved by molecular replacement and phase extension.

Citovat

PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN a Michael G. ROSSMANN. Structure determination of enterovirus 71. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. HOBOKEN: WILEY-BLACKWELL, 2012, roč. 68, September, s. 1217-1222. ISSN 0907-4449. Dostupné z: https://dx.doi.org/10.1107/S0907444912025772.

@article{1376812,
   author = {Plevka, Pavel and Perera, Rushika and Cardosa, Jane and Kuhn, Richard J. and Rossmann, Michael G.},
   article_location = {HOBOKEN},
   article_number = {September},
   doi = {http://dx.doi.org/10.1107/S0907444912025772},
   keywords = {COMMON COLD VIRUS; DECAY-ACCELERATING FACTOR; HUMAN RHINOVIRUS-14; COXSACKIEVIRUS B3; POLIOVIRUS; CRYSTALLOGRAPHY; PICORNAVIRUS; RESOLUTION; SOFTWARE; MALAYSIA},
   language = {eng},
   issn = {0907-4449},
   journal = {ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY},
   title = {Structure determination of enterovirus 71},
   volume = {68},
   year = {2012}
}

TY  - JOUR
ID  - 1376812
AU  - Plevka, Pavel - Perera, Rushika - Cardosa, Jane - Kuhn, Richard J. - Rossmann, Michael G.
PY  - 2012
TI  - Structure determination of enterovirus 71
JF  - ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
VL  - 68
IS  - September
SP  - 1217-1222
EP  - 1217-1222
PB  - WILEY-BLACKWELL
SN  - 09074449
KW  - COMMON COLD VIRUS
KW  - DECAY-ACCELERATING FACTOR
KW  - HUMAN RHINOVIRUS-14
KW  - COXSACKIEVIRUS B3
KW  - POLIOVIRUS
KW  - CRYSTALLOGRAPHY
KW  - PICORNAVIRUS
KW  - RESOLUTION
KW  - SOFTWARE
KW  - MALAYSIA
N2  - Enterovirus 71 is a picornavirus that causes hand, foot and mouth disease but may induce fatal neurological illness in infants and young children. Enterovirus 71 crystallized in a body-centered orthorhombic space group with two particles in general orientations in the crystallographic asymmetric unit. Determination of the particle orientations required that the locked rotation function excluded the twofold symmetry axes from the set of icosahedral symmetry operators. This avoided the occurrence of misleading high rotation-function values produced by the alignment of icosahedral and crystallographic twofold axes. Once the orientations and positions of the particles had been established, the structure was solved by molecular replacement and phase extension.
ER  -

PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN a Michael G. ROSSMANN. Structure determination of enterovirus 71. \textit{ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY}. HOBOKEN: WILEY-BLACKWELL, 2012, roč.~68, September, s.~1217-1222. ISSN~0907-4449. Dostupné z: https://dx.doi.org/10.1107/S0907444912025772.

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