DĚD, Tadeáš, David ŠAFRÁNEK, Matej TROJÁK, Matej KLEMENT, Jakub ŠALAGOVIČ and Luboš BRIM. Formal Biochemical Space with Semantics in Kappa and BNGL. Online. In Loic Pauleve et al. The 6th International Workshop on Static Analysis and Systems Biology, SASB 2015. ENTCS 326. Neuveden: Elsevier, 2016, p. 27-49. ISSN 1571-0661. Available from: https://dx.doi.org/10.1016/j.entcs.2016.09.017.
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Basic information
Original name Formal Biochemical Space with Semantics in Kappa and BNGL
Authors DĚD, Tadeáš (203 Czech Republic, belonging to the institution), David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution), Matej TROJÁK (703 Slovakia, belonging to the institution), Matej KLEMENT (703 Slovakia, belonging to the institution), Jakub ŠALAGOVIČ (703 Slovakia, belonging to the institution) and Luboš BRIM (203 Czech Republic, belonging to the institution).
Edition ENTCS 326. Neuveden, The 6th International Workshop on Static Analysis and Systems Biology, SASB 2015, p. 27-49, 23 pp. 2016.
Publisher Elsevier
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
RIV identification code RIV/00216224:14330/16:00088812
Organization unit Faculty of Informatics
ISSN 1571-0661
Doi http://dx.doi.org/10.1016/j.entcs.2016.09.017
UT WoS 000386589900003
Keywords in English Kappa; Biochemical space; CMP; cyanobacteria processes
Tags International impact, Reviewed
Changed by Changed by: RNDr. Pavel Šmerk, Ph.D., učo 3880. Changed: 13/5/2020 19:19.
Abstract
Biochemical Space (BCS) has been introduced as a semi-formal notation for reaction networks of biological processes. It provides a concise mapping of mathematical models to their biological description established at a desired level of abstraction. In this paper, we first turn BCS into a completely formal language with rigorously defined semantics by means of a simplified Kappa calculus. On the practical end, we support BCS with translation to BNGL, a well-known practically used rule-based language. Finally, we show the current status of BCS defined for cyanobacteria processes.
Links
GA15-11089S, research and development projectName: Získávání parametrů biologických modelů pomocí techniky ověřování modelů
Investor: Czech Science Foundation
LM2015055, research and development projectName: Centrum pro systémovou biologii (Acronym: C4SYS)
Investor: Ministry of Education, Youth and Sports of the CR
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