| HOFER, M, Z HOFEROVA, Daniel DEPEŠ a Martin FALK. Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review. Molecules. BASEL: Mayer und Muller, 2017, roč. 22, č. 5, 14 s. ISSN 1420-3049. Dostupné z: https://dx.doi.org/10.3390/molecules22050834. |
Další formáty:
BibTeX
LaTeX
RIS
@article{1382063,
author = {Hofer, M and Hoferova, Z and Depeš, Daniel and Falk, Martin},
article_location = {BASEL},
article_number = {5},
doi = {http://dx.doi.org/10.3390/molecules22050834},
keywords = {acute radiation syndrome; radioprotectors; radiomitigators; combined treatment; cytokines},
language = {eng},
issn = {1420-3049},
journal = {Molecules},
title = {Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review},
url = {http://dx.doi.org/10.3390/molecules22050834},
volume = {22},
year = {2017}
}
TY - JOUR
ID - 1382063
AU - Hofer, M - Hoferova, Z - Depeš, Daniel - Falk, Martin
PY - 2017
TI - Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review
JF - Molecules
VL - 22
IS - 5
PB - Mayer und Muller
SN - 14203049
KW - acute radiation syndrome
KW - radioprotectors
KW - radiomitigators
KW - combined treatment
KW - cytokines
UR - http://dx.doi.org/10.3390/molecules22050834
L2 - http://dx.doi.org/10.3390/molecules22050834
N2 - The goal of combined pharmacological approaches in the treatment of the acute radiation syndrome (ARS) is to obtain an effective therapy producing a minimum of undesirable side effects. This review summarizes important data from studies evaluating the efficacy of combining radioprotective agents developed for administration prior to irradiation and therapeutic agents administered in a post-irradiation treatment regimen. Many of the evaluated results show additivity, or even synergism, of the combined treatments in comparison with the effects of the individual component administrations. It can be deduced from these findings that the research in which combined treatments with radioprotectors/ radiomitigators are explored, tested, and evaluated is well-founded. The requirement for studies highly emphasizing the need to minimize undesirable side effects of the radioprotective/ radiomitigating therapies is stressed.
ER -
HOFER, M, Z HOFEROVA, Daniel DEPEŠ a Martin FALK. Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review. \textit{Molecules}. BASEL: Mayer und Muller, 2017, roč.~22, č.~5, 14 s. ISSN~1420-3049. Dostupné z: https://dx.doi.org/10.3390/molecules22050834.
|
