Association of the postoperative white blood cells (WBC) count
in peripheral blood after radical surgical treatment of left
upper lobe non-small cell lung cancer (NSCLC) with overall
survival - single center results

J 2017

Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results

BENEJ, Michal, Ivan ČAPOV, Jana SKŘIČKOVÁ, Karel HEJDUK, Adam PEŠTÁL et. al.

Základní údaje

Originální název

Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results

Autoři

BENEJ, Michal (703 Slovensko, garant), Ivan ČAPOV (203 Česká republika), Jana SKŘIČKOVÁ (203 Česká republika), Karel HEJDUK (203 Česká republika, domácí), Adam PEŠTÁL (203 Česká republika), Jan WECHSLER (203 Česká republika), H. ČOUPKOVÁ (203 Česká republika) a V. HYTYCH (203 Česká republika)

Vydání

Bratislava Medical Journal - Bratislavské lekárske listy, Bratislava, Univerzita Komenského, 2017, 0006-9248

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Slovensko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.678

Kód RIV

RIV/00216224:14110/17:00097053

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.4149/BLL_2017_073

UT WoS

000403031700010

Klíčová slova anglicky

postoperative white blood cells; peripheral blood; radical surgical treatment; left upper lobe; non-small cell lung cancer; survival-single center results

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 17. 5. 2018 16:18, Soňa Böhmová

Anotace

V originále

INTRODUCTION: The individual patient prognosis after radical surgery for Non-small cell lung cancer (NSCLC) of left upper lobe remains still unclear. The purpose of this study is to evaluate the predictive value of elevated white blood cell count in peripheral blood as early indicator of postoperative NSCLC prognosis. METHODS: A retrospective statistical analysis was performed studying patients subject to radical treatment of left upper lobe NSCLC in period of five years with subsequent one to three-year monitoring of morbidity and mortality of the patient population. The statistical ROC (Receiver Operating Characteristic) analysis of the WBC count in peripheral blood third day after the operation was used to evaluate the relationship with overall survival, with respect to patients surviving for at least 24 months. RESULTS: Based on the results of the ROC analysis with a total area under the curve (AUC) of 0.67, it is possible to confirm that the WBC count established third day after the operation allows us to classify patients into groups according to the 24-month overall survival. CONCLUSION: Our findings confirm the potential of using WBC count to improve current protocols to establish postoperative prognosis for NSCLC of the upper left lobe (Tab. 2, Fig. 1, Ref. 11). Text in PDF www.elis.sk.

Citovat

BENEJ, Michal, Ivan ČAPOV, Jana SKŘIČKOVÁ, Karel HEJDUK, Adam PEŠTÁL, Jan WECHSLER, H. ČOUPKOVÁ a V. HYTYCH. Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results. Bratislava Medical Journal - Bratislavské lekárske listy. Bratislava: Univerzita Komenského, 2017, roč. 118, č. 5, s. 299-301. ISSN 0006-9248. Dostupné z: https://dx.doi.org/10.4149/BLL_2017_073.

@article{1383810,
   author = {Benej, Michal and Čapov, Ivan and Skřičková, Jana and Hejduk, Karel and Peštál, Adam and Wechsler, Jan and Čoupková, H. and Hytych, V.},
   article_location = {Bratislava},
   article_number = {5},
   doi = {http://dx.doi.org/10.4149/BLL_2017_073},
   keywords = {postoperative white blood cells; peripheral blood; radical surgical treatment; left upper lobe; non-small cell lung cancer; survival-single center results},
   language = {eng},
   issn = {0006-9248},
   journal = {Bratislava Medical Journal - Bratislavské lekárske listy},
   title = {Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results},
   volume = {118},
   year = {2017}
}

TY  - JOUR
ID  - 1383810
AU  - Benej, Michal - Čapov, Ivan - Skřičková, Jana - Hejduk, Karel - Peštál, Adam - Wechsler, Jan - Čoupková, H. - Hytych, V.
PY  - 2017
TI  - Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results
JF  - Bratislava Medical Journal - Bratislavské lekárske listy
VL  - 118
IS  - 5
SP  - 299-301
EP  - 299-301
PB  - Univerzita Komenského
SN  - 00069248
KW  - postoperative white blood cells
KW  - peripheral blood
KW  - radical surgical treatment
KW  - left upper lobe
KW  - non-small cell lung cancer
KW  - survival-single center results
N2  - INTRODUCTION: The individual patient prognosis after radical surgery for Non-small cell lung cancer (NSCLC) of left upper lobe remains still unclear. The purpose of this study is to evaluate the predictive value of elevated white blood cell count in peripheral blood as early indicator of postoperative NSCLC prognosis. METHODS: A retrospective statistical analysis was performed studying patients subject to radical treatment of left upper lobe NSCLC in period of five years with subsequent one to three-year monitoring of morbidity and mortality of the patient population. The statistical ROC (Receiver Operating Characteristic) analysis of the WBC count in peripheral blood third day after the operation was used to evaluate the relationship with overall survival, with respect to patients surviving for at least 24 months. RESULTS: Based on the results of the ROC analysis with a total area under the curve (AUC) of 0.67, it is possible to confirm that the WBC count established third day after the operation allows us to classify patients into groups according to the 24-month overall survival. CONCLUSION: Our findings confirm the potential of using WBC count to improve current protocols to establish postoperative prognosis for NSCLC of the upper left lobe (Tab. 2, Fig. 1, Ref. 11). Text in PDF www.elis.sk.
ER  -

BENEJ, Michal, Ivan ČAPOV, Jana SKŘIČKOVÁ, Karel HEJDUK, Adam PEŠTÁL, Jan WECHSLER, H. ČOUPKOVÁ a V. HYTYCH. Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results. \textit{Bratislava Medical Journal - Bratislavské lekárske listy}. Bratislava: Univerzita Komenského, 2017, roč.~118, č.~5, s.~299-301. ISSN~0006-9248. Dostupné z: https://dx.doi.org/10.4149/BLL\_{}2017\_{}073.

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