Emotion recognition and theory of mind in schizophrenia: A meta-analysis of neuroimaging studies

JÁNI, Martin and Tomáš KAŠPÁREK. Emotion recognition and theory of mind in schizophrenia: A meta-analysis of neuroimaging studies. The World Journal of Biological Psychiatry. Abingdon: Taylor & Francis LTD, 2018, vol. 19, Suppl. 3, p. "S86"-"S96", 11 pp. ISSN 1562-2975. Available from: https://dx.doi.org/10.1080/15622975.2017.1324176.

Basic information

• Original name: Emotion recognition and theory of mind in schizophrenia: A meta-analysis of neuroimaging studies
• Authors: JÁNI, Martin (703 Slovakia, belonging to the institution) and Tomáš KAŠPÁREK (203 Czech Republic, guarantor, belonging to the institution).
• Edition: The World Journal of Biological Psychiatry, Abingdon, Taylor & Francis LTD, 2018, 1562-2975.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30215 Psychiatry
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 4.040
• RIV identification code: RIV/00216224:14110/18:00102006
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1080/15622975.2017.1324176
• UT WoS: 000453869700002
• Keywords in English: Behaviour; brain imaging; schizophrenia; social cognition; empathy
• Tags: 14110222, podil, rivok
• Tags: International impact, Reviewed

Abstract

Objectives: Patients with schizophrenia have difficulties processing the emotional and cognitive states of others. Neuroimaging studies show inconsistent findings. Methods: We used a Seed-based d Mapping meta-analytic method to explore brain activation during facial emotion recognition and theory of mind tasks in schizophrenia patients. Results: The patients showed lesser recruitment of the facial emotion processing network; behavioural performance was associated with the activation of the precentral gyrus. We found abnormal activation of the mentalising network in schizophrenia patients during reasoning about other people's mental states; patients with worse performances showed lesser activation in the right insula and superior temporal gyrus. Multimodal meta-analysis showed overlaps of brain-related abnormalities for both modalities in schizophrenia, with reduced recruitment of the right insula, anterior cingulate and medial prefrontal cortex and increased activation in the bilateral parietal cortex. Meta-regression results indicate that illness duration, medication and symptomatology might influence social-cognitive network disruptions in schizophrenia. Conclusions: These findings suggest the complex impairment of social cognition, as demonstrated by neural-related circuit disruptions during facial emotion processing and theory of mind tasks in schizophrenia.

Links

• LQ1601, research and development project: Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

• MUNI/A/1240/2014, interní kód MU: Name: Implementace behaviorálních paradigmat pro zobrazování a volbu neurostimulačních protokolů v psychiatrii. (Acronym: BEHAVIMG)

Investor: Masaryk University, Category A