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@article{1386732,
author = {Farka, Zdeněk and Juřík, Tomáš and Kovář, David and Trnková, Libuše and Skládal, Petr},
article_location = {Washington, D.C., USA},
article_number = {15},
doi = {http://dx.doi.org/10.1021/acs.chemrev.7b00037},
keywords = {Immunosensor; Immunoassay; Nanoparticle; Antibody},
language = {eng},
issn = {0009-2665},
journal = {Chemical Reviews},
title = {Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges},
url = {http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037},
volume = {117},
year = {2017}
}
TY - JOUR
ID - 1386732
AU - Farka, Zdeněk - Juřík, Tomáš - Kovář, David - Trnková, Libuše - Skládal, Petr
PY - 2017
TI - Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges
JF - Chemical Reviews
VL - 117
IS - 15
SP - 9973-10042
EP - 9973-10042
PB - American Chemical Society
SN - 00092665
KW - Immunosensor
KW - Immunoassay
KW - Nanoparticle
KW - Antibody
UR - http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037
L2 - http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037
N2 - We review the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The initial part introduces antibodies as classic recognition elements. The optical sensing part describes fluorescent, luminescent, and surface plasmon resonance systems. Amperometry, voltammetry, and impedance spectroscopy represent electrochemical transducer methods; electrochemiluminescence with photoelectric conversion constitutes a widely utilized combined method. The transducing options function together with suitable nanoparticles: metallic and metal oxides, including magnetic ones, carbon-based nanotubes, graphene variants, luminescent carbon dots, nanocrystals as quantum dots, and photon up-converting particles. These sources merged together provide extreme variability of existing nanoimmunosensing options. Finally, applications in clinical analysis (markers, tumor cells, and pharmaceuticals) and in the detection of pathogenic microorganisms, toxic agents, and pesticides in the environmental field and food products are summarized.
ER -
FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Libuše TRNKOVÁ a Petr SKLÁDAL. Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges. \textit{Chemical Reviews}. Washington, D.C., USA: American Chemical Society, 2017, roč.~117, č.~15, s.~9973-10042. ISSN~0009-2665. Dostupné z: https://dx.doi.org/10.1021/acs.chemrev.7b00037.
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