2017
Recent Findings of the Types of Programmed Cell Death
BORYS, Sylwia, Ronza KHOZMI, Wieslawa KRANS, Artur BRYJA, Marta DYSZKIEWICZ-KONWIŃSKA et. al.Základní údaje
Originální název
Recent Findings of the Types of Programmed Cell Death
Autoři
BORYS, Sylwia (616 Polsko), Ronza KHOZMI (616 Polsko), Wieslawa KRANS (616 Polsko), Artur BRYJA (616 Polsko), Marta DYSZKIEWICZ-KONWIŃSKA (616 Polsko), Michal JEŠETA (203 Česká republika, garant, domácí) a Bartosz KEMPISTY (616 Polsko)
Vydání
Advances in Cell Biology, Warsaw, Polskie towarzystwo anatomiczne, 2017, 0324-833X
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30214 Obstetrics and gynaecology
Stát vydavatele
Polsko
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 0.147
Kód RIV
RIV/00216224:14110/17:00097424
Organizační jednotka
Lékařská fakulta
Klíčová slova anglicky
apoptosis; mitochondrial apoptosis pathway; necrosis; receptor-dependent apotposis; pathway
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 20. 3. 2018 16:29, Soňa Böhmová
Anotace
V originále
Cell death plays an important role in maintaining the homeostasis of multicellular organisms. It can occur in a controlled manner by apoptosis or autophagy. Cell death which occurs regardless of regulatory factors include necrosis, mitotic catastrophe or oncosis. Apoptosis and necrosis are cellular process that leads to cell death. However their mechanisms are different, although factors triggering them can be similar. Necrosis and apoptosis have many different characteristics in terms of biochemistry and morphology. There are two main pathways of apoptosis induction signal: Receptor - dependent and mitochondrial. The outsider apoptotic pathway is induced by external factors stimulating membrane receptors having an intracellular domain called death domain. Mitochondrial apoptotic pathway is activated by increased concentration of reactive oxygen species (ROS), DNA damage, disorders electrolyte transport and an increase in the concentration of the calcium ions in the cytoplasm. In response to stress-factors, mitochondrial channels are opened, so that is released into the cytoplasm cytochrome C. This work is aimed at an overall description of exchanged processes.