Impaired baroreflex function during orthostatic challenge in
patients after spinal cord injury

J 2017

Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ et. al.

Základní údaje

Originální název

Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury

Autoři

ONDRUŠOVÁ, Katarína (703 Slovensko, domácí), Jana SVAČINOVÁ (203 Česká republika, domácí), Michal JAVORKA (703 Slovensko), Jan NOVÁK (203 Česká republika, domácí), Marie NOVÁKOVÁ (203 Česká republika, domácí) a Zuzana NOVÁKOVÁ (203 Česká republika, garant, domácí)

Vydání

Journal of Neurotrauma, New York, Mary Ann Liebert, 2017, 0897-7151

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.002

Kód RIV

RIV/00216224:14110/17:00097487

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1089/neu.2017.4989

UT WoS

000417633700007

Klíčová slova česky

Citlivost baroreflexu; poranění míchy; ortostáza; kauzální analýza

Klíčová slova anglicky

Baroreflex sensitivity; spinal cord injury; orthostasis; causal analysis

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 3. 2018 16:31, Soňa Böhmová

Anotace

V originále

The level of spinal cord injury affects baroreflex regulation of blood pressure. While a parasympathetic cardiac chronotropic effect is preserved, baroreflex response could be impaired by sympathetic dysfunction under the SCI level. This study was aimed to evaluate the baroreflex function in spinal cord injury patients by the analysis of causal interaction between systolic blood pressure and inter-beat intervals. Baroreflex dysfunction in spinal cord injury patients was detected using causal analysis methods during orthostatic challenge only. Baroreflex dysfunction is probably an important mechanism of the more expressed blood pressure decrease associated with cervical spinal cord injury. The severity of autonomic dysfunction was related to spinal cord injury level.

Návaznosti

MUNI/A/1355/2016, interní kód MU

Název: Kardiovaskulární systém očima molekulární fyziologie

Investor: Masarykova univerzita, Kardiovaskulární systém očima molekulární fyziologie, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ a Zuzana NOVÁKOVÁ. Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury. Journal of Neurotrauma. New York: Mary Ann Liebert, 2017, roč. 34, č. 24, s. 3381-3387. ISSN 0897-7151. Dostupné z: https://dx.doi.org/10.1089/neu.2017.4989.

@article{1388731,
   author = {Ondrušová, Katarína and Svačinová, Jana and Javorka, Michal and Novák, Jan and Nováková, Marie and Nováková, Zuzana},
   article_location = {New York},
   article_number = {24},
   doi = {http://dx.doi.org/10.1089/neu.2017.4989},
   keywords = {Baroreflex sensitivity; spinal cord injury; orthostasis; causal analysis},
   language = {eng},
   issn = {0897-7151},
   journal = {Journal of Neurotrauma},
   title = {Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury},
   volume = {34},
   year = {2017}
}

TY  - JOUR
ID  - 1388731
AU  - Ondrušová, Katarína - Svačinová, Jana - Javorka, Michal - Novák, Jan - Nováková, Marie - Nováková, Zuzana
PY  - 2017
TI  - Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury
JF  - Journal of Neurotrauma
VL  - 34
IS  - 24
SP  - 3381-3387
EP  - 3381-3387
PB  - Mary Ann Liebert
SN  - 08977151
KW  - Baroreflex sensitivity
KW  - spinal cord injury
KW  - orthostasis
KW  - causal analysis
N2  - The level of spinal cord injury affects baroreflex regulation of blood pressure. While a parasympathetic cardiac chronotropic effect is preserved, baroreflex response could be impaired by sympathetic dysfunction under the SCI level. This study was aimed to evaluate the baroreflex function in spinal cord injury patients by the analysis of causal interaction between systolic blood pressure and inter-beat intervals. Baroreflex dysfunction in spinal cord injury patients was detected using causal analysis methods during orthostatic challenge only. Baroreflex dysfunction is probably an important mechanism of the more expressed blood pressure decrease associated with cervical spinal cord injury. The severity of autonomic dysfunction was related to spinal cord injury level.
ER  -

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ a Zuzana NOVÁKOVÁ. Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury. \textit{Journal of Neurotrauma}. New York: Mary Ann Liebert, 2017, roč.~34, č.~24, s.~3381-3387. ISSN~0897-7151. Dostupné z: https://dx.doi.org/10.1089/neu.2017.4989.

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