a 2017

Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus

PLESKAČOVÁ, Anna, Monika SKRUTKOVÁ LANGMAJEROVÁ, Jindra SMUTNÁ, Vendula BARTÁKOVÁ, Katarína CHALÁSOVÁ et. al.

Základní údaje

Originální název

Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus

Název anglicky

Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus

Autoři

Vydání

53rd Annual Meeting of the European Association for the Study of Diabtes, 2017

Další údaje

Typ výsledku

Konferenční abstrakt

Utajení

není předmětem státního či obchodního tajemství

Klíčová slova anglicky

Gestational diabetes mellitus, amino acid, free fatty acid, metabolism

Příznaky

Mezinárodní význam
Změněno: 26. 9. 2017 17:03, Mgr. Anna Kolouchová, Ph.D.

Anotace

V originále

The increasing prevalence of gestational diabetes mellitus (GDM) poses a risk for permanent diabetes development in future life for both mother and child. We hypothesize, that changes in non-esterified fatty acids (NEFAs) and amino acids (AAs) in plasma previously associated with type 2 diabetes development may reflect more severe abnormalities in insulin secretion and sensitivity and thus may point at more severe disturbance in glucose tolerance during pregnancy. The aims of this study were to determine NEFAs (C12:0 to C22:6) and all proteinogenic and several nonessential AAs during pregnancy and postpartum period in women with GDM and those with physiological pregnancy and to study the relationships between selected metabolites and anthropometrical and biochemical data.

Anglicky

The increasing prevalence of gestational diabetes mellitus (GDM) poses a risk for permanent diabetes development in future life for both mother and child. We hypothesize, that changes in non-esterified fatty acids (NEFAs) and amino acids (AAs) in plasma previously associated with type 2 diabetes development may reflect more severe abnormalities in insulin secretion and sensitivity and thus may point at more severe disturbance in glucose tolerance during pregnancy. The aims of this study were to determine NEFAs (C12:0 to C22:6) and all proteinogenic and several nonessential AAs during pregnancy and postpartum period in women with GDM and those with physiological pregnancy and to study the relationships between selected metabolites and anthropometrical and biochemical data.

Návaznosti

NV16-28040A, projekt VaV
Název: Dlouhodobé dopady gestačního diabetes mellitus pro metabolické zdraví žen časně postpartum: význam nových diagnostických kritérií