2017
Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus
PLESKAČOVÁ, Anna, Monika SKRUTKOVÁ LANGMAJEROVÁ, Jindra SMUTNÁ, Vendula BARTÁKOVÁ, Katarína CHALÁSOVÁ et. al.Základní údaje
Originální název
Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus
Název anglicky
Changes in lipid and amino acid levels during pregnancy and early postpartum period in pregnancy complicated by gestational diabetes mellitus
Autoři
PLESKAČOVÁ, Anna, Monika SKRUTKOVÁ LANGMAJEROVÁ, Jindra SMUTNÁ, Vendula BARTÁKOVÁ, Katarína CHALÁSOVÁ, Lukáš PÁCAL, Josef TOMANDL a Kateřina KAŇKOVÁ
Vydání
53rd Annual Meeting of the European Association for the Study of Diabtes, 2017
Další údaje
Typ výsledku
Konferenční abstrakt
Utajení
není předmětem státního či obchodního tajemství
Klíčová slova anglicky
Gestational diabetes mellitus, amino acid, free fatty acid, metabolism
Příznaky
Mezinárodní význam
Změněno: 26. 9. 2017 17:03, Mgr. Anna Kolouchová, Ph.D.
V originále
The increasing prevalence of gestational diabetes mellitus (GDM) poses a risk for permanent diabetes development in future life for both mother and child. We hypothesize, that changes in non-esterified fatty acids (NEFAs) and amino acids (AAs) in plasma previously associated with type 2 diabetes development may reflect more severe abnormalities in insulin secretion and sensitivity and thus may point at more severe disturbance in glucose tolerance during pregnancy. The aims of this study were to determine NEFAs (C12:0 to C22:6) and all proteinogenic and several nonessential AAs during pregnancy and postpartum period in women with GDM and those with physiological pregnancy and to study the relationships between selected metabolites and anthropometrical and biochemical data.
Anglicky
The increasing prevalence of gestational diabetes mellitus (GDM) poses a risk for permanent diabetes development in future life for both mother and child. We hypothesize, that changes in non-esterified fatty acids (NEFAs) and amino acids (AAs) in plasma previously associated with type 2 diabetes development may reflect more severe abnormalities in insulin secretion and sensitivity and thus may point at more severe disturbance in glucose tolerance during pregnancy. The aims of this study were to determine NEFAs (C12:0 to C22:6) and all proteinogenic and several nonessential AAs during pregnancy and postpartum period in women with GDM and those with physiological pregnancy and to study the relationships between selected metabolites and anthropometrical and biochemical data.
Návaznosti
| NV16-28040A, projekt VaV |
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