KOJECKÝ, Vladimír, J. MATOUS, R. KEIL, Milan DASTYCH, Radek KROUPA, Z. ZADOROVA, M. VARGA, Jiří DOLINA, M. KMENT a Aleš HEP. A head-to-head comparison of 4-L polyethylene glycol and low-volume solutions before colonoscopy: which is the best? A multicentre, randomized trial. International Journal of Colorectal Disease. New York: Springer, 2017, roč. 32, č. 12, s. 1763-1766. ISSN 0179-1958. Dostupné z: https://dx.doi.org/10.1007/s00384-017-2901-x. |
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@article{1396180, author = {Kojecký, Vladimír and Matous, J. and Keil, R. and Dastych, Milan and Kroupa, Radek and Zadorova, Z. and Varga, M. and Dolina, Jiří and Kment, M. and Hep, Aleš}, article_location = {New York}, article_number = {12}, doi = {http://dx.doi.org/10.1007/s00384-017-2901-x}, keywords = {Ascorbic acid; Colonoscopy; Magnesium citrate; Picosulfate sodium; Polyethylene glycol}, language = {eng}, issn = {0179-1958}, journal = {International Journal of Colorectal Disease}, title = {A head-to-head comparison of 4-L polyethylene glycol and low-volume solutions before colonoscopy: which is the best? A multicentre, randomized trial}, volume = {32}, year = {2017} }
TY - JOUR ID - 1396180 AU - Kojecký, Vladimír - Matous, J. - Keil, R. - Dastych, Milan - Kroupa, Radek - Zadorova, Z. - Varga, M. - Dolina, Jiří - Kment, M. - Hep, Aleš PY - 2017 TI - A head-to-head comparison of 4-L polyethylene glycol and low-volume solutions before colonoscopy: which is the best? A multicentre, randomized trial JF - International Journal of Colorectal Disease VL - 32 IS - 12 SP - 1763-1766 EP - 1763-1766 PB - Springer SN - 01791958 KW - Ascorbic acid KW - Colonoscopy KW - Magnesium citrate KW - Picosulfate sodium KW - Polyethylene glycol N2 - Purpose: The purpose of this study is to compare the efficacy and tolerability of polyethylene glycol (PEG) to sodium picosulfate/magnesium citrate (SPMC) and low-volume polyethylene glycol/ascorbic acid (PEGA) in a single- or split-dose regimen for colonoscopy bowel preparation. Methods: This was a prospective, randomized, endoscopist-blinded, multicentre study. Outpatients received either PEG or SPMC or PEGA in a single or a split dose before the colonoscopy. Quality and tolerability of the preparation and complaints during preparation were recorded. Results: Nine hundred seventy-three patients were analysed. Satisfactory bowel cleansing (Aronchick score 1 + 2) was more frequent when a split dose was used irrespective of the solution type (PEG 90.1 vs 68.8%, PEGA 86.0 vs 71.6%, SPMC 84.3 vs 60.2%, p < 0.001). SPMC was the best tolerated followed by PEGA (p < 0.006) and PEG as the worst (p < 0.001). Tolerability did not correlate with the regimen and amount of the solution used. Female gender is associated with a higher incidence of nausea, vomiting and pain (p < 0.029). Conclusions: Both PEG, PEGA and SPMC are fully comparable in terms of colonic cleansing when used in similar regimens. The split-dose preparation is more effective in all agents. SPMC and PEGA are better tolerated than PEG. The preparation regimen and/or the volume do not affect tolerability. ER -
KOJECKÝ, Vladimír, J. MATOUS, R. KEIL, Milan DASTYCH, Radek KROUPA, Z. ZADOROVA, M. VARGA, Jiří DOLINA, M. KMENT a Aleš HEP. A head-to-head comparison of 4-L polyethylene glycol and low-volume solutions before colonoscopy: which is the best? A multicentre, randomized trial. \textit{International Journal of Colorectal Disease}. New York: Springer, 2017, roč.~32, č.~12, s.~1763-1766. ISSN~0179-1958. Dostupné z: https://dx.doi.org/10.1007/s00384-017-2901-x.
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