24-Hour Alberta Stroke Program Early CT Score Assessment in
Post-Stroke Spasticity Development in Patients with a First
Documented Anterior Circulation Ischemic Stroke

J 2018

24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke

VOLNÝ, Ondřej, Mária JUSTANOVÁ, Petra CIMFLOVÁ, Linda MACHOVÁ, Ivana SVOBODOVÁ et. al.

Základní údaje

Originální název

24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke

Autoři

VOLNÝ, Ondřej (203 Česká republika, garant, domácí), Mária JUSTANOVÁ (203 Česká republika, domácí), Petra CIMFLOVÁ (203 Česká republika, domácí), Linda MACHOVÁ (203 Česká republika), Ivana SVOBODOVÁ (203 Česká republika, domácí), Jan MUŽÍK (203 Česká republika, domácí) a Martin BAREŠ (203 Česká republika, domácí)

Vydání

Journal of Stroke and Cerebrovascular Diseases, Amsterdam, Elsevier Science BV. 2018, 1052-3057

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.646

Kód RIV

RIV/00216224:14110/18:00102114

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.08.033

UT WoS

000419584400033

Klíčová slova anglicky

Middle cerebral artery territory; Modified; Ashworth scale; Post-stroke spasticity; Stroke

Štítky

14110119, 14110127, 14119612, EL OK, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 13. 9. 2021 15:01, Mgr. Tereza Miškechová

Anotace

V originále

Background: Neuroanatomic substrates responsible for development of post-stroke spasticity are still poorly understood. The study is focused on identification of brain regions within the territory of the middle cerebral artery associated with spasticity development. Methods: This is a single-center prospective cohort study of first documented anterior circulation ischemic strokes with a neurologic deficit lasting >7 days (from March 2014 to September 2016, all patients are involved in a registry). Ischemic cerebral lesions within the territory of middle cerebral artery were evaluated using the Alberta Stroke Program Early CT Score (ASPECTS) on control 24-hour computed tomography or magnetic resonance imaging. Spasticity was assessed with modified Ashworth scale. Results: Seventy-six patients (mean age 72 years, 45% females; 30% treated with IV tissue plasminogen activator, 6.5% mechanical thrombectomy) fulfilled the study inclusion criteria. Forty-nine (64%) developed early elbow or wrist flexor spasticity defined as modified Ashworth scale >1 (at day 7-10), in 44 (58%) the spasticity remained present at 6 months. There were no differences between the patients who developed spasticity and those who did not when comparing admission stroke severity (National Institutes of Health Stroke Scale 5 [interquartile range (IQR) 4-8] versus 6 [IQR 4-10]) and vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, coronary artery disease). Nor was there a difference in 24-hour ASPECTS score (9 [IQR 8-10] versus 9 [IQR 7-10]). No differences were found between the groups with and without the early upper limb flexor spasticity of particular regions (M1, M2, M3, M4, M5, M6, lentiform, insula, caudate, internal capsule) and precentral-postcentral gyrus, premotor cortex, supplementary motor area, posterior limb of internal capsule, and thalamus were compared. Conclusions: We did not find any middle cerebral artery territory associated with post-stroke spasticity development by detailed evaluation of ASPECTS.

Citovat

VOLNÝ, Ondřej, Mária JUSTANOVÁ, Petra CIMFLOVÁ, Linda MACHOVÁ, Ivana SVOBODOVÁ, Jan MUŽÍK a Martin BAREŠ. 24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases. Amsterdam: Elsevier Science BV., 2018, roč. 27, č. 1, s. 240-245. ISSN 1052-3057. Dostupné z: https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.08.033.

@article{1396994,
   author = {Volný, Ondřej and Justanová, Mária and Cimflová, Petra and Machová, Linda and Svobodová, Ivana and Mužík, Jan and Bareš, Martin},
   article_location = {Amsterdam},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.08.033},
   keywords = {Middle cerebral artery territory; Modified; Ashworth scale; Post-stroke spasticity; Stroke},
   language = {eng},
   issn = {1052-3057},
   journal = {Journal of Stroke and Cerebrovascular Diseases},
   title = {24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke},
   url = {https://www.sciencedirect.com/science/article/pii/S1052305717304548?via%3Dihub},
   volume = {27},
   year = {2018}
}

TY  - JOUR
ID  - 1396994
AU  - Volný, Ondřej - Justanová, Mária - Cimflová, Petra - Machová, Linda - Svobodová, Ivana - Mužík, Jan - Bareš, Martin
PY  - 2018
TI  - 24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke
JF  - Journal of Stroke and Cerebrovascular Diseases
VL  - 27
IS  - 1
SP  - 240-245
EP  - 240-245
PB  - Elsevier Science BV.
SN  - 10523057
KW  - Middle cerebral artery territory
KW  - Modified
KW  - Ashworth scale
KW  - Post-stroke spasticity
KW  - Stroke
UR  - https://www.sciencedirect.com/science/article/pii/S1052305717304548?via%3Dihub
N2  - Background: Neuroanatomic substrates responsible for development of post-stroke spasticity are still poorly understood. The study is focused on identification of brain regions within the territory of the middle cerebral artery associated with spasticity development. Methods: This is a single-center prospective cohort study of first documented anterior circulation ischemic strokes with a neurologic deficit lasting >7 days (from March 2014 to September 2016, all patients are involved in a registry). Ischemic cerebral lesions within the territory of middle cerebral artery were evaluated using the Alberta Stroke Program Early CT Score (ASPECTS) on control 24-hour computed tomography or magnetic resonance imaging. Spasticity was assessed with modified Ashworth scale. Results: Seventy-six patients (mean age 72 years, 45% females; 30% treated with IV tissue plasminogen activator, 6.5% mechanical thrombectomy) fulfilled the study inclusion criteria. Forty-nine (64%) developed early elbow or wrist flexor spasticity defined as modified Ashworth scale >1 (at day 7-10), in 44 (58%) the spasticity remained present at 6 months. There were no differences between the patients who developed spasticity and those who did not when comparing admission stroke severity (National Institutes of Health Stroke Scale 5 [interquartile range (IQR) 4-8] versus 6 [IQR 4-10]) and vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, coronary artery disease). Nor was there a difference in 24-hour ASPECTS score (9 [IQR 8-10] versus 9 [IQR 7-10]). No differences were found between the groups with and without the early upper limb flexor spasticity of particular regions (M1, M2, M3, M4, M5, M6, lentiform, insula, caudate, internal capsule) and precentral-postcentral gyrus, premotor cortex, supplementary motor area, posterior limb of internal capsule, and thalamus were compared. Conclusions: We did not find any middle cerebral artery territory associated with post-stroke spasticity development by detailed evaluation of ASPECTS.
ER  -

VOLNÝ, Ondřej, Mária JUSTANOVÁ, Petra CIMFLOVÁ, Linda MACHOVÁ, Ivana SVOBODOVÁ, Jan MUŽÍK a Martin BAREŠ. 24-Hour Alberta Stroke Program Early CT Score Assessment in Post-Stroke Spasticity Development in Patients with a First Documented Anterior Circulation Ischemic Stroke. \textit{Journal of Stroke and Cerebrovascular Diseases}. Amsterdam: Elsevier Science BV., 2018, roč.~27, č.~1, s.~240-245. ISSN~1052-3057. Dostupné z: https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.08.033.

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