Effect of a 6-month pedometer-based walking intervention on
functional capacity in patients with chronic heart failure with
reduced (HFrEF) and with preserved (HFpEF) ejection fraction:
study protocol for two multicenter randomized controlled trials

J 2017

Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials

VETROVSKY, T., M. SIRANEC, Jiří PAŘENICA, M. GRIVA, J. STASTNY et. al.

Základní údaje

Originální název

Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials

Autoři

VETROVSKY, T., M. SIRANEC, Jiří PAŘENICA, M. GRIVA, J. STASTNY, J. PRECEK, R. PELOUCH, V. BUNC, A. LINHART a J. BELOHLAVEK

Vydání

Journal of Translational Medicine, London, England, BIOMED CENTRAL LTD, 2017, 1479-5876

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.197

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1186/s12967-017-1257-x

UT WoS

000405770300002

Klíčová slova anglicky

Chronic heart failure; Physical activity; Walking; Functional capacity; Pedometer; 6-min walk test; NT-proBNP

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 3. 2018 16:24, Soňa Böhmová

Anotace

V originále

Background: Regular physical activity is recommended for patients with chronic heart failure to improve their functional capacity, and walking is a popular, effective, and safe form of physical activity. Pedometers have shown potential to increase the amount of walking across a range of chronic diseases, but it is unknown whether a pedometerbased intervention improves functional capacity and neurohumoral modulation in heart failure patients. Methods: Two multicenter randomized controlled trials will be conducted in parallel: one in patients with chronic heart failure with reduced ejection fraction (HFrEF), the other in patients with chronic heart failure with preserved ejection fraction (HFpEF). Each trial will consist of a 6-month intervention with an assessment at baseline, at 3 months, at the end of the intervention, and 6 months after completing the intervention. Each trial will aim to include a total of 200 physically inactive participants with chronic heart failure who will be randomly assigned to intervention or control arms. The 6-month intervention will consist of an individualized pedometer-based walking program with weekly step goals, behavioral face-to-face sessions with a physician, and regular telephone calls with a research nurse. The intervention will be based on effective behavioral principles (goal setting, self-monitoring, personalized feedback). The primary outcome is the change in 6-min walk distance at the end of the 6-month intervention. Secondary outcomes include changes in serum biomarkers levels, pulmonary congestion assessed by ultrasound, average daily step count measured by accelerometry, anthropometric measures, symptoms of depression, health-related quality of life, self-efficacy, and MAGGIC risk score. Discussion: To our knowledge, these are the first studies to evaluate a pedometer-based walking intervention in patients with chronic heart failure with either reduced or preserved ejection fraction. The studies will contribute to a better understanding of physical activity promotion in heart failure patients to inform future physical activity recommendations and heart failure guidelines.

Citovat

VETROVSKY, T., M. SIRANEC, Jiří PAŘENICA, M. GRIVA, J. STASTNY, J. PRECEK, R. PELOUCH, V. BUNC, A. LINHART a J. BELOHLAVEK. Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials. Journal of Translational Medicine. London, England: BIOMED CENTRAL LTD, 2017, roč. 15, č. 153, s. 1-10. ISSN 1479-5876. Dostupné z: https://dx.doi.org/10.1186/s12967-017-1257-x.

@article{1397230,
   author = {Vetrovsky, T. and Siranec, M. and Pařenica, Jiří and Griva, M. and Stastny, J. and Precek, J. and Pelouch, R. and Bunc, V. and Linhart, A. and Belohlavek, J.},
   article_location = {London, England},
   article_number = {153},
   doi = {http://dx.doi.org/10.1186/s12967-017-1257-x},
   keywords = {Chronic heart failure; Physical activity; Walking; Functional capacity; Pedometer; 6-min walk test; NT-proBNP},
   language = {eng},
   issn = {1479-5876},
   journal = {Journal of Translational Medicine},
   title = {Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials},
   url = {http://dx.doi.org/10.1186/s12967-017-1257-x},
   volume = {15},
   year = {2017}
}

TY  - JOUR
ID  - 1397230
AU  - Vetrovsky, T. - Siranec, M. - Pařenica, Jiří - Griva, M. - Stastny, J. - Precek, J. - Pelouch, R. - Bunc, V. - Linhart, A. - Belohlavek, J.
PY  - 2017
TI  - Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials
JF  - Journal of Translational Medicine
VL  - 15
IS  - 153
SP  - 1-10
EP  - 1-10
PB  - BIOMED CENTRAL LTD
SN  - 14795876
KW  - Chronic heart failure
KW  - Physical activity
KW  - Walking
KW  - Functional capacity
KW  - Pedometer
KW  - 6-min walk test
KW  - NT-proBNP
UR  - http://dx.doi.org/10.1186/s12967-017-1257-x
L2  - http://dx.doi.org/10.1186/s12967-017-1257-x
N2  - Background: Regular physical activity is recommended for patients with chronic heart failure to improve their functional capacity, and walking is a popular, effective, and safe form of physical activity. Pedometers have shown potential to increase the amount of walking across a range of chronic diseases, but it is unknown whether a pedometerbased intervention improves functional capacity and neurohumoral modulation in heart failure patients. Methods: Two multicenter randomized controlled trials will be conducted in parallel: one in patients with chronic heart failure with reduced ejection fraction (HFrEF), the other in patients with chronic heart failure with preserved ejection fraction (HFpEF). Each trial will consist of a 6-month intervention with an assessment at baseline, at 3 months, at the end of the intervention, and 6 months after completing the intervention. Each trial will aim to include a total of 200 physically inactive participants with chronic heart failure who will be randomly assigned to intervention or control arms. The 6-month intervention will consist of an individualized pedometer-based walking program with weekly step goals, behavioral face-to-face sessions with a physician, and regular telephone calls with a research nurse. The intervention will be based on effective behavioral principles (goal setting, self-monitoring, personalized feedback). The primary outcome is the change in 6-min walk distance at the end of the 6-month intervention. Secondary outcomes include changes in serum biomarkers levels, pulmonary congestion assessed by ultrasound, average daily step count measured by accelerometry, anthropometric measures, symptoms of depression, health-related quality of life, self-efficacy, and MAGGIC risk score. Discussion: To our knowledge, these are the first studies to evaluate a pedometer-based walking intervention in patients with chronic heart failure with either reduced or preserved ejection fraction. The studies will contribute to a better understanding of physical activity promotion in heart failure patients to inform future physical activity recommendations and heart failure guidelines.
ER  -

VETROVSKY, T., M. SIRANEC, Jiří PAŘENICA, M. GRIVA, J. STASTNY, J. PRECEK, R. PELOUCH, V. BUNC, A. LINHART a J. BELOHLAVEK. Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials. \textit{Journal of Translational Medicine}. London, England: BIOMED CENTRAL LTD, 2017, roč.~15, č.~153, s.~1-10. ISSN~1479-5876. Dostupné z: https://dx.doi.org/10.1186/s12967-017-1257-x.

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