OCT guidance during stent implantation in primary PCI: A
randomized multicenter study with nine months of optical
coherence tomography follow-up

J 2018

OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up

KALA, Petr, P. CERVINKA, M. JAKL, Jan KAŇOVSKÝ, A. KUPEC et. al.

Základní údaje

Originální název

OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up

Autoři

KALA, Petr (203 Česká republika, domácí), P. CERVINKA (203 Česká republika, garant), M. JAKL (203 Česká republika), Jan KAŇOVSKÝ (203 Česká republika, domácí), A. KUPEC (203 Česká republika), R. SPACEK (203 Česká republika), M. KVASNAK (203 Česká republika), Martin POLOCZEK (203 Česká republika), M. CERVINKOVA (203 Česká republika), H. BEZERRA (840 Spojené státy), Z. VALENTA (203 Česká republika), G.F. ATTIZZANI (840 Spojené státy), A. SCHNELL (840 Spojené státy), L. HONG (840 Spojené státy) a M.A. COSTA (840 Spojené státy)

Vydání

International Journal of Cardiology, Clare (Ireland), Elsevier Ireland Ltd. 2018, 0167-5273

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.471

Kód RIV

RIV/00216224:14110/18:00102131

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ijcard.2017.10.059

UT WoS

000415822100021

Klíčová slova anglicky

Optical coherence tomography; OCT; Primary PCI; ST-segment elevation myocardial infarction; Drug-eluting stents

Štítky

14110211, EL OK, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 2. 2019 17:03, Soňa Böhmová

Anotace

V originále

Aims: To assess the possible merits of optical coherence tomography (OCT) guidance in primary percutaneous coronary intervention (pPCI). Methods and results: 201 patients with ST-elevation myocardial infarction (STEMI) were enrolled in this study. Patients were randomized either to pPCI alone (angio-guided group, n = 96) or to pPCI with OCT guidance (OCT-guided group, n = 105) and also either to biolimus A9 or to everolimus-eluting stent implantation. All patients were scheduled for nine months of follow-up angiography and OCT study. OCT guidance led to post-pPCI optimization in 29% of cases (59% malapposition and 41% dissections). No complications were found related to the OCT study. OCT analysis at ninemonths showed significantly less in-segment area of stenosis (6% [-11, 19] versus 18% [3, 33]; p = 0.0002) in favor of the OCT-guided group. The rate major adverse cardiovascular events were comparable at nine months in both groups (3% in the OCT group versus 2% in the angio-guided group; p = 0.87). Conclusions: This study demonstrates the safety of OCT guidance during pPCI. The use of OCT optimized stent deployment in 1/3 of patients in this clinical scenario and significantly reduced in-segment area of stenosis at nine months of follow-up. Whether such improvements in OCT endpoints will have a positive impact on late clinical outcomes, they demand both a larger and longer-term follow-up study. (C) 2017 Elsevier B.V. All rights reserved.

Citovat

KALA, Petr, P. CERVINKA, M. JAKL, Jan KAŇOVSKÝ, A. KUPEC, R. SPACEK, M. KVASNAK, Martin POLOCZEK, M. CERVINKOVA, H. BEZERRA, Z. VALENTA, G.F. ATTIZZANI, A. SCHNELL, L. HONG a M.A. COSTA. OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up. International Journal of Cardiology. Clare (Ireland): Elsevier Ireland Ltd., 2018, roč. 250, JAN 1 2018, s. 98-103. ISSN 0167-5273. Dostupné z: https://dx.doi.org/10.1016/j.ijcard.2017.10.059.

@article{1398905,
   author = {Kala, Petr and Cervinka, P. and Jakl, M. and Kaňovský, Jan and Kupec, A. and Spacek, R. and Kvasnak, M. and Poloczek, Martin and Cervinkova, M. and Bezerra, H. and Valenta, Z. and Attizzani, G.F. and Schnell, A. and Hong, L. and Costa, M.A.},
   article_location = {Clare (Ireland)},
   article_number = {JAN 1 2018},
   doi = {http://dx.doi.org/10.1016/j.ijcard.2017.10.059},
   keywords = {Optical coherence tomography; OCT; Primary PCI; ST-segment elevation myocardial infarction; Drug-eluting stents},
   language = {eng},
   issn = {0167-5273},
   journal = {International Journal of Cardiology},
   title = {OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up},
   volume = {250},
   year = {2018}
}

TY  - JOUR
ID  - 1398905
AU  - Kala, Petr - Cervinka, P. - Jakl, M. - Kaňovský, Jan - Kupec, A. - Spacek, R. - Kvasnak, M. - Poloczek, Martin - Cervinkova, M. - Bezerra, H. - Valenta, Z. - Attizzani, G.F. - Schnell, A. - Hong, L. - Costa, M.A.
PY  - 2018
TI  - OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up
JF  - International Journal of Cardiology
VL  - 250
IS  - JAN 1 2018
SP  - 98-103
EP  - 98-103
PB  - Elsevier Ireland Ltd.
SN  - 01675273
KW  - Optical coherence tomography
KW  - OCT
KW  - Primary PCI
KW  - ST-segment elevation myocardial infarction
KW  - Drug-eluting stents
N2  - Aims: To assess the possible merits of optical coherence tomography (OCT) guidance in primary percutaneous coronary intervention (pPCI). Methods and results: 201 patients with ST-elevation myocardial infarction (STEMI) were enrolled in this study. Patients were randomized either to pPCI alone (angio-guided group, n = 96) or to pPCI with OCT guidance (OCT-guided group, n = 105) and also either to biolimus A9 or to everolimus-eluting stent implantation. All patients were scheduled for nine months of follow-up angiography and OCT study. OCT guidance led to post-pPCI optimization in 29% of cases (59% malapposition and 41% dissections). No complications were found related to the OCT study. OCT analysis at ninemonths showed significantly less in-segment area of stenosis (6% [-11, 19] versus 18% [3, 33]; p = 0.0002) in favor of the OCT-guided group. The rate major adverse cardiovascular events were comparable at nine months in both groups (3% in the OCT group versus 2% in the angio-guided group; p = 0.87). Conclusions: This study demonstrates the safety of OCT guidance during pPCI. The use of OCT optimized stent deployment in 1/3 of patients in this clinical scenario and significantly reduced in-segment area of stenosis at nine months of follow-up. Whether such improvements in OCT endpoints will have a positive impact on late clinical outcomes, they demand both a larger and longer-term follow-up study. (C) 2017 Elsevier B.V. All rights reserved.
ER  -

KALA, Petr, P. CERVINKA, M. JAKL, Jan KAŇOVSKÝ, A. KUPEC, R. SPACEK, M. KVASNAK, Martin POLOCZEK, M. CERVINKOVA, H. BEZERRA, Z. VALENTA, G.F. ATTIZZANI, A. SCHNELL, L. HONG a M.A. COSTA. OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up. \textit{International Journal of Cardiology}. Clare (Ireland): Elsevier Ireland Ltd., 2018, roč.~250, JAN 1 2018, s.~98-103. ISSN~0167-5273. Dostupné z: https://dx.doi.org/10.1016/j.ijcard.2017.10.059.

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