Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes
in a Pooled Analysis of Case-Control Studies

J 2017

Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies

OLSSON, A.C., R. VERMEULEN, J. SCHUZ, H. KROMHOUT, B. PESCH et. al.

Základní údaje

Originální název

Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies

Autoři

OLSSON, A.C. (250 Francie), R. VERMEULEN (528 Nizozemské království), J. SCHUZ (250 Francie), H. KROMHOUT (528 Nizozemské království), B. PESCH (276 Německo), S. PETERS (250 Francie), T. BEHRENS (276 Německo), L. PORTENGEN (250 Francie), D. MIRABELLI (752 Švédsko), P. GUSTAVSSON (752 Švédsko), B. KENDZIA (276 Německo), J. ALMANSA (528 Nizozemské království), V. LUZON (250 Francie), J. VLAANDEREN (250 Francie), I. STUCKER (250 Francie), F. GUIDA (250 Francie), D. CONSONNI (380 Itálie), N. CAPORASO (840 Spojené státy), M.T. LANDI (840 Spojené státy), J. FIELD (826 Velká Británie a Severní Irsko), I. BRUSKE (276 Německo), H.E. WICHMANN (276 Německo), J. SIEMIATYCKI (124 Kanada), M.E. PARENT (124 Kanada), L. RICHIARDI (380 Itálie), F. MERLETTI (380 Itálie), K.H. JOCKEL (276 Německo), W. AHRENS (276 Německo), H. POHLABELN (276 Německo), N. PLATO (752 Švédsko), A. TARDON (724 Španělsko), D. ZARIDZE (643 Rusko), J. MCLAUGHLIN (124 Kanada), P. DEMERS (124 Kanada), N. SZESZENIA-DABROWSKA (616 Polsko), J. LISSOWSKA (616 Polsko), P. RUDNAI (348 Maďarsko), E. FABIANOVA (703 Slovensko), R.S. DUMITRU (642 Rumunsko), V. BENCKO (203 Česká republika), Lenka FORETOVÁ (203 Česká republika, garant, domácí), V. JANOUT (203 Česká republika), P. BOFFETTA (840 Spojené státy), B. BUENO-DE-MESQUITA (528 Nizozemské království), F. FORASTIERE (380 Itálie), T. BRUNING (276 Německo) a K. STRAIF (250 Francie)

Vydání

Epidemiology, Philadelphia (USA), Lippincott Williams and Wilkins, 2017, 1044-3983

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30305 Occupational health

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.991

Kód RIV

RIV/00216224:14110/17:00098731

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1097/EDE.0000000000000604

UT WoS

000393959000027

Klíčová slova anglicky

Lung Cancer

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 3. 2018 16:52, Soňa Böhmová

Anotace

V originále

Background: Evidence is limited regarding risk and the shape of the exposure-response curve at low asbestos exposure levels. We estimated the exposure-response for occupational asbestos exposure and assessed the joint effect of asbestos exposure and smoking by sex and lung cancer subtype in general population studies. Methods: We pooled 14 case-control studies conducted in 19852010 in Europe and Canada, including 17,705 lung cancer cases and 21,813 controls with detailed information on tobacco habits and lifetime occupations. We developed a quantitative job-exposure-matrix to estimate job-, time period-, and region-specific exposure levels. Fiber-years (ff/ml-years) were calculated for each subject by linking the matrix with individual occupational histories. We fit unconditional logistic regression models to estimate odds ratios (ORs), 95% confidence intervals (CIs), and trends. Results: The fully adjusted OR for ever-exposure to asbestos was 1.24 (95% CI, 1.18, 1.31) in men and 1.12 (95% CI, 0.95, 1.31) in women. In men, increasing lung cancer risk was observed with increasing exposure in all smoking categories and for all three major lung cancer subtypes. In women, lung cancer risk for all subtypes was increased in current smokers (ORs similar to two-fold). The joint effect of asbestos exposure and smoking did not deviate from multiplicativity among men, and was more than additive among women. Conclusions: Our results in men showed an excess risk of lung cancer and its subtypes at low cumulative exposure levels, with a steeper exposure-response slope in this exposure range than at higher, previously studied levels. (See video abstract at, http://links.lww.com/EDE/B161.)

Citovat

OLSSON, A.C., R. VERMEULEN, J. SCHUZ, H. KROMHOUT, B. PESCH, S. PETERS, T. BEHRENS, L. PORTENGEN, D. MIRABELLI, P. GUSTAVSSON, B. KENDZIA, J. ALMANSA, V. LUZON, J. VLAANDEREN, I. STUCKER, F. GUIDA, D. CONSONNI, N. CAPORASO, M.T. LANDI, J. FIELD, I. BRUSKE, H.E. WICHMANN, J. SIEMIATYCKI, M.E. PARENT, L. RICHIARDI, F. MERLETTI, K.H. JOCKEL, W. AHRENS, H. POHLABELN, N. PLATO, A. TARDON, D. ZARIDZE, J. MCLAUGHLIN, P. DEMERS, N. SZESZENIA-DABROWSKA, J. LISSOWSKA, P. RUDNAI, E. FABIANOVA, R.S. DUMITRU, V. BENCKO, Lenka FORETOVÁ, V. JANOUT, P. BOFFETTA, B. BUENO-DE-MESQUITA, F. FORASTIERE, T. BRUNING a K. STRAIF. Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies. Epidemiology. Philadelphia (USA): Lippincott Williams and Wilkins, 2017, roč. 28, č. 2, s. 288-299. ISSN 1044-3983. Dostupné z: https://dx.doi.org/10.1097/EDE.0000000000000604.

@article{1398986,
   author = {Olsson, A.C. and Vermeulen, R. and Schuz, J. and Kromhout, H. and Pesch, B. and Peters, S. and Behrens, T. and Portengen, L. and Mirabelli, D. and Gustavsson, P. and Kendzia, B. and Almansa, J. and Luzon, V. and Vlaanderen, J. and Stucker, I. and Guida, F. and Consonni, D. and Caporaso, N. and Landi, M.T. and Field, J. and Bruske, I. and Wichmann, H.E. and Siemiatycki, J. and Parent, M.E. and Richiardi, L. and Merletti, F. and Jockel, K.H. and Ahrens, W. and Pohlabeln, H. and Plato, N. and Tardon, A. and Zaridze, D. and McLaughlin, J. and Demers, P. and SzeszeniaandDabrowska, N. and Lissowska, J. and Rudnai, P. and Fabianova, E. and Dumitru, R.S. and Bencko, V. and Foretová, Lenka and Janout, V. and Boffetta, P. and BuenoandDeandMesquita, B. and Forastiere, F. and Bruning, T. and Straif, K.},
   article_location = {Philadelphia (USA)},
   article_number = {2},
   doi = {http://dx.doi.org/10.1097/EDE.0000000000000604},
   keywords = {Lung Cancer},
   language = {eng},
   issn = {1044-3983},
   journal = {Epidemiology},
   title = {Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies},
   volume = {28},
   year = {2017}
}

TY  - JOUR
ID  - 1398986
AU  - Olsson, A.C. - Vermeulen, R. - Schuz, J. - Kromhout, H. - Pesch, B. - Peters, S. - Behrens, T. - Portengen, L. - Mirabelli, D. - Gustavsson, P. - Kendzia, B. - Almansa, J. - Luzon, V. - Vlaanderen, J. - Stucker, I. - Guida, F. - Consonni, D. - Caporaso, N. - Landi, M.T. - Field, J. - Bruske, I. - Wichmann, H.E. - Siemiatycki, J. - Parent, M.E. - Richiardi, L. - Merletti, F. - Jockel, K.H. - Ahrens, W. - Pohlabeln, H. - Plato, N. - Tardon, A. - Zaridze, D. - McLaughlin, J. - Demers, P. - Szeszenia-Dabrowska, N. - Lissowska, J. - Rudnai, P. - Fabianova, E. - Dumitru, R.S. - Bencko, V. - Foretová, Lenka - Janout, V. - Boffetta, P. - Bueno-De-Mesquita, B. - Forastiere, F. - Bruning, T. - Straif, K.
PY  - 2017
TI  - Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies
JF  - Epidemiology
VL  - 28
IS  - 2
SP  - 288-299
EP  - 288-299
PB  - Lippincott Williams and Wilkins
SN  - 10443983
KW  - Lung Cancer
N2  - Background: Evidence is limited regarding risk and the shape of the exposure-response curve at low asbestos exposure levels. We estimated the exposure-response for occupational asbestos exposure and assessed the joint effect of asbestos exposure and smoking by sex and lung cancer subtype in general population studies. Methods: We pooled 14 case-control studies conducted in 19852010 in Europe and Canada, including 17,705 lung cancer cases and 21,813 controls with detailed information on tobacco habits and lifetime occupations. We developed a quantitative job-exposure-matrix to estimate job-, time period-, and region-specific exposure levels. Fiber-years (ff/ml-years) were calculated for each subject by linking the matrix with individual occupational histories. We fit unconditional logistic regression models to estimate odds ratios (ORs), 95% confidence intervals (CIs), and trends. Results: The fully adjusted OR for ever-exposure to asbestos was 1.24 (95% CI, 1.18, 1.31) in men and 1.12 (95% CI, 0.95, 1.31) in women. In men, increasing lung cancer risk was observed with increasing exposure in all smoking categories and for all three major lung cancer subtypes. In women, lung cancer risk for all subtypes was increased in current smokers (ORs similar to two-fold). The joint effect of asbestos exposure and smoking did not deviate from multiplicativity among men, and was more than additive among women. Conclusions: Our results in men showed an excess risk of lung cancer and its subtypes at low cumulative exposure levels, with a steeper exposure-response slope in this exposure range than at higher, previously studied levels. (See video abstract at, http://links.lww.com/EDE/B161.)
ER  -

OLSSON, A.C., R. VERMEULEN, J. SCHUZ, H. KROMHOUT, B. PESCH, S. PETERS, T. BEHRENS, L. PORTENGEN, D. MIRABELLI, P. GUSTAVSSON, B. KENDZIA, J. ALMANSA, V. LUZON, J. VLAANDEREN, I. STUCKER, F. GUIDA, D. CONSONNI, N. CAPORASO, M.T. LANDI, J. FIELD, I. BRUSKE, H.E. WICHMANN, J. SIEMIATYCKI, M.E. PARENT, L. RICHIARDI, F. MERLETTI, K.H. JOCKEL, W. AHRENS, H. POHLABELN, N. PLATO, A. TARDON, D. ZARIDZE, J. MCLAUGHLIN, P. DEMERS, N. SZESZENIA-DABROWSKA, J. LISSOWSKA, P. RUDNAI, E. FABIANOVA, R.S. DUMITRU, V. BENCKO, Lenka FORETOVÁ, V. JANOUT, P. BOFFETTA, B. BUENO-DE-MESQUITA, F. FORASTIERE, T. BRUNING a K. STRAIF. Exposure-Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case-Control Studies. \textit{Epidemiology}. Philadelphia (USA): Lippincott Williams and Wilkins, 2017, roč.~28, č.~2, s.~288-299. ISSN~1044-3983. Dostupné z: https://dx.doi.org/10.1097/EDE.0000000000000604.

Podrobný výpis o publikaci