Umbilical cord blood and maternal visfatin (PBEF/NAMPT)
concentrations in preterm birth with and without preterm
premature rupture of membranes

J 2018

Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes

PAVLOVÁ, Tereza, Filip ZLÁMAL, Zbyněk ŠPLÍCHAL, Josef TOMANDL, Zuzana HODICKÁ et. al.

Základní údaje

Originální název

Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes

Autoři

PAVLOVÁ, Tereza (203 Česká republika, garant, domácí), Filip ZLÁMAL (203 Česká republika, domácí), Zbyněk ŠPLÍCHAL (203 Česká republika, domácí), Josef TOMANDL (203 Česká republika, domácí), Zuzana HODICKÁ (203 Česká republika), Pavel VENTRUBA (203 Česká republika) a Julie BIENERTOVÁ VAŠKŮ (203 Česká republika, domácí)

Vydání

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, LONDON, INFORMA HEALTHCARE, 2018, 1476-7058

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.569

Kód RIV

RIV/00216224:14110/18:00102133

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1080/14767058.2017.1328493

UT WoS

000430732700001

Klíčová slova anglicky

Visfatin; PBEF; NAMPT; preterm birth; preterm premature rupture of membranes

Štítky

14110512, 14110518, EL OK, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 3. 2019 10:35, Soňa Böhmová

Anotace

V originále

Objectives: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs).Methods: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM).Results: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p=.021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p=.027; p=.039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p=.007).Conclusions: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

Citovat

PAVLOVÁ, Tereza, Filip ZLÁMAL, Zbyněk ŠPLÍCHAL, Josef TOMANDL, Zuzana HODICKÁ, Pavel VENTRUBA a Julie BIENERTOVÁ VAŠKŮ. Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. LONDON: INFORMA HEALTHCARE, 2018, roč. 31, č. 14, s. 1811-1818. ISSN 1476-7058. Dostupné z: https://dx.doi.org/10.1080/14767058.2017.1328493.

@article{1399107,
   author = {Pavlová, Tereza and Zlámal, Filip and Šplíchal, Zbyněk and Tomandl, Josef and Hodická, Zuzana and Ventruba, Pavel and Bienertová Vašků, Julie},
   article_location = {LONDON},
   article_number = {14},
   doi = {http://dx.doi.org/10.1080/14767058.2017.1328493},
   keywords = {Visfatin; PBEF; NAMPT; preterm birth; preterm premature rupture of membranes},
   language = {eng},
   issn = {1476-7058},
   journal = {JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE},
   title = {Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes},
   volume = {31},
   year = {2018}
}

TY  - JOUR
ID  - 1399107
AU  - Pavlová, Tereza - Zlámal, Filip - Šplíchal, Zbyněk - Tomandl, Josef - Hodická, Zuzana - Ventruba, Pavel - Bienertová Vašků, Julie
PY  - 2018
TI  - Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes
JF  - JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
VL  - 31
IS  - 14
SP  - 1811-1818
EP  - 1811-1818
PB  - INFORMA HEALTHCARE
SN  - 14767058
KW  - Visfatin
KW  - PBEF
KW  - NAMPT
KW  - preterm birth
KW  - preterm premature rupture of membranes
N2  - Objectives: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs).Methods: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM).Results: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p=.021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p=.027; p=.039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p=.007).Conclusions: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.
ER  -

PAVLOVÁ, Tereza, Filip ZLÁMAL, Zbyněk ŠPLÍCHAL, Josef TOMANDL, Zuzana HODICKÁ, Pavel VENTRUBA a Julie BIENERTOVÁ VAŠKŮ. Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes. \textit{JOURNAL OF MATERNAL-FETAL \&{}amp; NEONATAL MEDICINE}. LONDON: INFORMA HEALTHCARE, 2018, roč.~31, č.~14, s.~1811-1818. ISSN~1476-7058. Dostupné z: https://dx.doi.org/10.1080/14767058.2017.1328493.

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