J 2017

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

NEČAS, Miroslav a Eliška DASTYCHOVÁ

Základní údaje

Originální název

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Autoři

NEČAS, Miroslav (203 Česká republika, garant, domácí) a Eliška DASTYCHOVÁ (203 Česká republika, domácí)

Vydání

International Journal of Ophthalmology and Clinical Research, Wilmington, ClinMed International Library, 2017, 2378-346X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30216 Dermatology and venereal diseases

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/17:00098829

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Periorbital dermatitis; Patch tests; Contact allergens

Štítky

Změněno: 17. 5. 2018 17:41, Soňa Böhmová

Anotace

V originále

Aims: 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization. Methods: A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results: The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion: The most important allergens in ophtalmolog-ic products in our study were neomycin sulfate followed by benzalkonium chloride. With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient's actual ophtalmic preparations as well.