NEČAS, Miroslav and Eliška DASTYCHOVÁ. Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic. International Journal of Ophthalmology and Clinical Research. Wilmington: ClinMed International Library, 2017, vol. 4, No 3, p. 1-5. ISSN 2378-346X.
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Basic information
Original name Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic
Authors NEČAS, Miroslav (203 Czech Republic, guarantor, belonging to the institution) and Eliška DASTYCHOVÁ (203 Czech Republic, belonging to the institution).
Edition International Journal of Ophthalmology and Clinical Research, Wilmington, ClinMed International Library, 2017, 2378-346X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30216 Dermatology and venereal diseases
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/17:00098829
Organization unit Faculty of Medicine
Keywords in English Periorbital dermatitis; Patch tests; Contact allergens
Tags EL OK
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 17/5/2018 17:41.
Abstract
Aims: 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization. Methods: A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results: The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion: The most important allergens in ophtalmolog-ic products in our study were neomycin sulfate followed by benzalkonium chloride. With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient's actual ophtalmic preparations as well.
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