Atypical handedness in mesial temporal lobe epilepsy

J 2017

Atypical handedness in mesial temporal lobe epilepsy

DOLEŽALOVÁ, Irena, S. SCHACHTER, Jan CHRASTINA, Jan HEMZA, Markéta HERMANOVÁ et. al.

Základní údaje

Originální název

Atypical handedness in mesial temporal lobe epilepsy

Autoři

DOLEŽALOVÁ, Irena (203 Česká republika, garant, domácí), S. SCHACHTER (840 Spojené státy), Jan CHRASTINA (203 Česká republika, domácí), Jan HEMZA (203 Česká republika, domácí), Markéta HERMANOVÁ (203 Česká republika, domácí), Ivan REKTOR (203 Česká republika, domácí), Marta PAŽOURKOVÁ (203 Česká republika, domácí) a Milan BRÁZDIL (203 Česká republika, domácí)

Vydání

EPILEPSY & BEHAVIOR, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, 1525-5050

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.600

Kód RIV

RIV/00216224:14110/17:00099039

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.yebeh.2017.01.034

UT WoS

000406321300014

Klíčová slova anglicky

Mesial temporal lobe epilepsy; Handedness; Left-handed; Right-handed; Age at epilepsy onset; Atypical dominance

Štítky

EL OK, podil

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 3. 2018 15:29, Soňa Böhmová

Anotace

V originále

Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p < 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE. (C) 2017 Elsevier Inc. All rights reserved.

Citovat

DOLEŽALOVÁ, Irena, S. SCHACHTER, Jan CHRASTINA, Jan HEMZA, Markéta HERMANOVÁ, Ivan REKTOR, Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč. 72, JUL 2017, s. 78-81. ISSN 1525-5050. Dostupné z: https://dx.doi.org/10.1016/j.yebeh.2017.01.034.

@article{1400988,
   author = {Doležalová, Irena and Schachter, S. and Chrastina, Jan and Hemza, Jan and Hermanová, Markéta and Rektor, Ivan and Pažourková, Marta and Brázdil, Milan},
   article_location = {SAN DIEGO},
   article_number = {JUL 2017},
   doi = {http://dx.doi.org/10.1016/j.yebeh.2017.01.034},
   keywords = {Mesial temporal lobe epilepsy; Handedness; Left-handed; Right-handed; Age at epilepsy onset; Atypical dominance},
   language = {eng},
   issn = {1525-5050},
   journal = {EPILEPSY & BEHAVIOR},
   title = {Atypical handedness in mesial temporal lobe epilepsy},
   volume = {72},
   year = {2017}
}

TY  - JOUR
ID  - 1400988
AU  - Doležalová, Irena - Schachter, S. - Chrastina, Jan - Hemza, Jan - Hermanová, Markéta - Rektor, Ivan - Pažourková, Marta - Brázdil, Milan
PY  - 2017
TI  - Atypical handedness in mesial temporal lobe epilepsy
JF  - EPILEPSY & BEHAVIOR
VL  - 72
IS  - JUL 2017
SP  - 78-81
EP  - 78-81
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN  - 15255050
KW  - Mesial temporal lobe epilepsy
KW  - Handedness
KW  - Left-handed
KW  - Right-handed
KW  - Age at epilepsy onset
KW  - Atypical dominance
N2  - Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p < 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE. (C) 2017 Elsevier Inc. All rights reserved.
ER  -

DOLEŽALOVÁ, Irena, S. SCHACHTER, Jan CHRASTINA, Jan HEMZA, Markéta HERMANOVÁ, Ivan REKTOR, Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. \textit{EPILEPSY \&{}amp; BEHAVIOR}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč.~72, JUL 2017, s.~78-81. ISSN~1525-5050. Dostupné z: https://dx.doi.org/10.1016/j.yebeh.2017.01.034.

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