BUDINSKAYA, Ksenia, Jana SVAČINOVÁ, Jana HRUŠKOVÁ, Zuzana KUBECOVÁ, Vojtěch SVÍZELA, Hana HRSTKOVÁ, Petr DOBŠÁK, Jana RYDLOVÁ, Kateřina LINHARTOVÁ and Zuzana NOVÁKOVÁ. Non-invasive estimation of arterial stiffness in healthy and asthmatic children - comparison of the methods: a pilot study. In Federation of Europian Physiological Societies 2017. 2017. ISSN 1748-1708.
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Basic information
Original name Non-invasive estimation of arterial stiffness in healthy and asthmatic children - comparison of the methods: a pilot study.
Name in Czech Neinvazivní stanovení parametrů cévní stěny u děti s astma bronchiale: pilotní studie.
Authors BUDINSKAYA, Ksenia, Jana SVAČINOVÁ, Jana HRUŠKOVÁ, Zuzana KUBECOVÁ, Vojtěch SVÍZELA, Hana HRSTKOVÁ, Petr DOBŠÁK, Jana RYDLOVÁ, Kateřina LINHARTOVÁ and Zuzana NOVÁKOVÁ.
Edition Federation of Europian Physiological Societies 2017, 2017.
Other information
Type of outcome Conference abstract
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 5.930
ISSN 1748-1708
UT WoS 000408842000143
Keywords in English arterial stiffness, pulse wave velocity, augmentation index, cardio-ankle index
Changed by Changed by: Xenie Budínská, Ph.D., učo 409542. Changed: 30/1/2018 13:20.
Abstract
Questions Asthma is an inflammatory disease that affects not only lungs but other organ system, e.g. a cardiovascular system. Arterial stiffness is a subclinical predictor of cardiovascular diseases. Its measurement is carried out by applanation tonometry (European countries) with such main parameters as pulse wave velocity (PWV) and augmentation index (AI) as well as measurement of Cardio-ankle index (CAVI) outside Europe. The aim of our study is to estimate arterial stiffness in asthmatic and healthy children using two methods of its measurement and compare them. Methods We measured asthmatic children (group A, 52 respondents) and control group (C, 71 respondents) of the same age, systolic (SBP), diastolic (DBP) blood pressure and body mass index (BMI). For each respondent we measured SPB, DPB, PWV, AI and AI standardized on pulse height and heart rate (AIx75) on the dominant side with Sphygmocor device (AtCor Medical, Australia). All measurements were calibrated by oscillometric blood pressure measurement on the brachial artery (Omron, HEM-907-E, Japan) on the same side. The CAVI was measured with VaSera device (Fukuda Denshi, Japan). The Statistic 13 software was used for statistical analysis. Result There were significant differences in AIx75 (3.0±10.9 vs. -2.0±10.6; p<0.05), PWV (6.6±1.1 vs. 7.2±1.4; p<0.05), CAVI (4.5±0.9 vs. 4.9±0.6; p<0.05) between A and C, and significant correlation between PWV and CAVI (p<0.05). Conclusion We can conclude that asthma bronchiale and its treatment changed the properties of vessels in children comparing to the healthy group. Our study shows that both methods reflect the changes in arterial stiffness.
Links
MUNI/A/1355/2016, interní kód MUName: Kardiovaskulární systém očima molekulární fyziologie
Investor: Masaryk University, Category A
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