| SVÁTKOVÁ, Alena, Bryon MUELLER, Petr BEDNAŘÍK, Carol NGUYEN, Lubomír VOJTÍŠEK, Silvia MANGIA, Mikko NISSI, Shalom MICHAELI a Igor NESTRAŠIL. Rotating Frame MRI Contrasts For Assessment of White Matter Alteration in Mucopolysaccharidosis Type I. In Joint annual meeting ISMRM-ESMRMB 2018. 2018. |
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@proceedings{1406319,
author = {Svátková, Alena and Mueller, Bryon and Bednařík, Petr and Nguyen, Carol and Vojtíšek, Lubomír and Mangia, Silvia and Nissi, Mikko and Michaeli, Shalom and Nestrašil, Igor},
booktitle = {Joint annual meeting ISMRM-ESMRMB 2018},
title = {Rotating Frame MRI Contrasts For Assessment of White Matter Alteration in Mucopolysaccharidosis Type I},
year = {2018}
}
TY - CONF
ID - 1406319
AU - Svátková, Alena - Mueller, Bryon - Bednařík, Petr - Nguyen, Carol - Vojtíšek, Lubomír - Mangia, Silvia - Nissi, Mikko - Michaeli, Shalom - Nestrašil, Igor
PY - 2018
TI - Rotating Frame MRI Contrasts For Assessment of White Matter Alteration in Mucopolysaccharidosis Type I
N2 - Mucopolysaccharidosis type I (MPSI) is an inherited metabolic disease with severe and attenuated disease subtypes. While both MPSI subtypes manifest pronounced morphological brain changes, little has been discovered about alterations of white matter (WM) microstructure. Here, we utilized rotating frame MRI contrasts along with DTI to detect WM alterations in 11 severe and 9 attenuated MPSI patients at 3T. T1ρ and RAFF4 detected WM differences between MPS subtypes that were not depicted by DTI. Outcomes demonstrate an exceptional sensitivity of rotating frame methods to probe WM microstructure in MPSI.
ER -
SVÁTKOVÁ, Alena, Bryon MUELLER, Petr BEDNAŘÍK, Carol NGUYEN, Lubomír VOJTÍŠEK, Silvia MANGIA, Mikko NISSI, Shalom MICHAELI a Igor NESTRAŠIL. Rotating Frame MRI Contrasts For Assessment of White Matter Alteration in Mucopolysaccharidosis Type I. In \textit{Joint annual meeting ISMRM-ESMRMB 2018}. 2018.
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