| ARAB, Anas, Anna WOJNA PELCZAR, Amit Suresh KHAIRNAR, Nikoletta SZABÓ a Jana RUDÁ. Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders. Brain Research Bulletin. Oxford: Pergamon-Elsevier Science LTD, 2018, roč. 139, MAY 2018, s. 91-98. ISSN 0361-9230. Dostupné z: https://dx.doi.org/10.1016/j.brainresbull.2018.01.015. |
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@article{1406888,
author = {Arab, Anas and Wojna Pelczar, Anna and Khairnar, Amit Suresh and Szabó, Nikoletta and Rudá, Jana},
article_location = {Oxford},
article_number = {MAY 2018},
doi = {http://dx.doi.org/10.1016/j.brainresbull.2018.01.015},
keywords = {Diffusion kurtosis imaging; neuroimaging; neurodegenerative disorders; Parkinson’s disease; Alzheimer’s disease; Huntington’s disease},
language = {eng},
issn = {0361-9230},
journal = {Brain Research Bulletin},
title = {Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders},
volume = {139},
year = {2018}
}
TY - JOUR
ID - 1406888
AU - Arab, Anas - Wojna Pelczar, Anna - Khairnar, Amit Suresh - Szabó, Nikoletta - Rudá, Jana
PY - 2018
TI - Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders
JF - Brain Research Bulletin
VL - 139
IS - MAY 2018
SP - 91-98
EP - 91-98
PB - Pergamon-Elsevier Science LTD
SN - 03619230
KW - Diffusion kurtosis imaging
KW - neuroimaging
KW - neurodegenerative disorders
KW - Parkinson’s disease
KW - Alzheimer’s disease
KW - Huntington’s disease
N2 - Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as extracellular changes which lead to neuronal degeneration. The central nervous system (CNS) is a complex structure comprising of many biological barriers. These microstructural barriers might be affected by a variety of pathological processes. Specifically, changes in the brain tissue’s microstructure affect the diffusion of water which can be assessed non-invasively by diffusion weighted (DW) magnetic resonance imaging (MRI) techniques. Hence, the purpose of this article is to summarize the ongoing clinical and preclinical research on Parkinson’s, Alzheimer’s and Huntington diseases, using DKI and to discuss the role of this technique as an early stage biomarker of neurodegenerative conditions.
ER -
ARAB, Anas, Anna WOJNA PELCZAR, Amit Suresh KHAIRNAR, Nikoletta SZABÓ a Jana RUDÁ. Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders. \textit{Brain Research Bulletin}. Oxford: Pergamon-Elsevier Science LTD, 2018, roč.~139, MAY 2018, s.~91-98. ISSN~0361-9230. Dostupné z: https://dx.doi.org/10.1016/j.brainresbull.2018.01.015.
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