Principles of Diffusion Kurtosis Imaging and its Role in Early
Diagnosis of Neurodegenerative Disorders

J 2018

Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders

ARAB, Anas, Anna WOJNA PELCZAR, Amit Suresh KHAIRNAR, Nikoletta SZABÓ, Jana RUDÁ et. al.

Základní údaje

Originální název

Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders

Název česky

Princip Diffusion Kurtosis Imaging a jeho role v časné diagnostice neurodegenerativních onemocnění

Autoři

ARAB, Anas (760 Sýrie, domácí), Anna WOJNA PELCZAR (616 Polsko, domácí), Amit Suresh KHAIRNAR (356 Indie, garant), Nikoletta SZABÓ (348 Maďarsko, domácí) a Jana RUDÁ (203 Česká republika, domácí)

Vydání

Brain Research Bulletin, Oxford, Pergamon-Elsevier Science LTD, 2018, 0361-9230

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.103

Kód RIV

RIV/00216224:14110/18:00102274

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.brainresbull.2018.01.015

UT WoS

000433651600011

Klíčová slova anglicky

Diffusion kurtosis imaging; neuroimaging; neurodegenerative disorders; Parkinson’s disease; Alzheimer’s disease; Huntington’s disease

Štítky

14110516, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 5. 2019 13:20, Soňa Böhmová

Anotace

V originále

Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as extracellular changes which lead to neuronal degeneration. The central nervous system (CNS) is a complex structure comprising of many biological barriers. These microstructural barriers might be affected by a variety of pathological processes. Specifically, changes in the brain tissue’s microstructure affect the diffusion of water which can be assessed non-invasively by diffusion weighted (DW) magnetic resonance imaging (MRI) techniques. Hence, the purpose of this article is to summarize the ongoing clinical and preclinical research on Parkinson’s, Alzheimer’s and Huntington diseases, using DKI and to discuss the role of this technique as an early stage biomarker of neurodegenerative conditions.

Návaznosti

MUNI/A/1132/2017, interní kód MU

Název: Behaviorální psychofarmakologie a farmakokinetika v preklinickém výzkumu léčiv

Investor: Masarykova univerzita, Behaviorální psychofarmakologie a farmakokinetika v preklinickém výzkumu léčiv, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

ARAB, Anas, Anna WOJNA PELCZAR, Amit Suresh KHAIRNAR, Nikoletta SZABÓ a Jana RUDÁ. Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders. Brain Research Bulletin. Oxford: Pergamon-Elsevier Science LTD, 2018, roč. 139, MAY 2018, s. 91-98. ISSN 0361-9230. Dostupné z: https://dx.doi.org/10.1016/j.brainresbull.2018.01.015.

@article{1406888,
   author = {Arab, Anas and Wojna Pelczar, Anna and Khairnar, Amit Suresh and Szabó, Nikoletta and Rudá, Jana},
   article_location = {Oxford},
   article_number = {MAY 2018},
   doi = {http://dx.doi.org/10.1016/j.brainresbull.2018.01.015},
   keywords = {Diffusion kurtosis imaging; neuroimaging; neurodegenerative disorders; Parkinson’s disease; Alzheimer’s disease; Huntington’s disease},
   language = {eng},
   issn = {0361-9230},
   journal = {Brain Research Bulletin},
   title = {Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders},
   volume = {139},
   year = {2018}
}

TY  - JOUR
ID  - 1406888
AU  - Arab, Anas - Wojna Pelczar, Anna - Khairnar, Amit Suresh - Szabó, Nikoletta - Rudá, Jana
PY  - 2018
TI  - Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders
JF  - Brain Research Bulletin
VL  - 139
IS  - MAY 2018
SP  - 91-98
EP  - 91-98
PB  - Pergamon-Elsevier Science LTD
SN  - 03619230
KW  - Diffusion kurtosis imaging
KW  - neuroimaging
KW  - neurodegenerative disorders
KW  - Parkinson’s disease
KW  - Alzheimer’s disease
KW  - Huntington’s disease
N2  - Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as extracellular changes which lead to neuronal degeneration. The central nervous system (CNS) is a complex structure comprising of many biological barriers. These microstructural barriers might be affected by a variety of pathological processes. Specifically, changes in the brain tissue’s microstructure affect the diffusion of water which can be assessed non-invasively by diffusion weighted (DW) magnetic resonance imaging (MRI) techniques. Hence, the purpose of this article is to summarize the ongoing clinical and preclinical research on Parkinson’s, Alzheimer’s and Huntington diseases, using DKI and to discuss the role of this technique as an early stage biomarker of neurodegenerative conditions.
ER  -

ARAB, Anas, Anna WOJNA PELCZAR, Amit Suresh KHAIRNAR, Nikoletta SZABÓ a Jana RUDÁ. Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders. \textit{Brain Research Bulletin}. Oxford: Pergamon-Elsevier Science LTD, 2018, roč.~139, MAY 2018, s.~91-98. ISSN~0361-9230. Dostupné z: https://dx.doi.org/10.1016/j.brainresbull.2018.01.015.

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