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@article{1407843,
author = {Sun, Xiaolong and Odyniec, Maria L. and Sedgwick, Adam C. and Lacina, Karel and Xu, Suying and Qiang, Taotao and Bull, Steven D. and Marken, Frank and James, Tony D.},
article_number = {6},
doi = {http://dx.doi.org/10.1039/c6qo00448b},
keywords = {FLUORESCENT-PROBES; LIVING CELLS; BORONIC ACID; IN-VIVO; INFLAMMATION; REPORTER; MODEL},
language = {eng},
issn = {2052-4129},
journal = {Organic Chemistry Frontiers},
title = {Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide},
url = {http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b},
volume = {4},
year = {2017}
}
TY - JOUR
ID - 1407843
AU - Sun, Xiaolong - Odyniec, Maria L. - Sedgwick, Adam C. - Lacina, Karel - Xu, Suying - Qiang, Taotao - Bull, Steven D. - Marken, Frank - James, Tony D.
PY - 2017
TI - Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide
JF - Organic Chemistry Frontiers
VL - 4
IS - 6
SP - 1058-1062
EP - 1058-1062
SN - 20524129
KW - FLUORESCENT-PROBES
KW - LIVING CELLS
KW - BORONIC ACID
KW - IN-VIVO
KW - INFLAMMATION
KW - REPORTER
KW - MODEL
UR - http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b
L2 - http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b
N2 - Based on the complexation of phenylboronic acid (PBA) with Alizarin Red S (ARS), we developed a new chemosensor for the detection of hydrogen peroxide (H2O2) in aqueous media. This platform has demonstrated its ability to detect H2O2 via colorimetric, fluorometric, and electrochemical measurements. The experimental observations reveal that the system displays a red-shifted visible colour change, on–off fluorescence response indicating release of indicator (ARS) and turn-on electrochemical signal indicating generation of phenol, after reaction with H2O2. With this work we have demonstrated that our reaction-based indicator displacement assay (RIA) systems, can be employed as an assay for H2O2 and hydrogen peroxide-related species for environmental and physiological detection.
ER -
SUN, Xiaolong, Maria L. ODYNIEC, Adam C. SEDGWICK, Karel LACINA, Suying XU, Taotao QIANG, Steven D. BULL, Frank MARKEN a Tony D. JAMES. Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide. \textit{Organic Chemistry Frontiers}. 2017, roč.~4, č.~6, s.~1058-1062. ISSN~2052-4129. Dostupné z: https://dx.doi.org/10.1039/c6qo00448b.
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