Evolutionarily Distant Streptophyta Respond Differently to
Genotoxic Stress

J 2017

Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress

VAGNEROVA, R., A. LUKESOVA, M. LUKES, P. ROZNOVSKA, M. HOLA et. al.

Základní údaje

Originální název

Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress

Autoři

VAGNEROVA, R. (203 Česká republika), A. LUKESOVA (203 Česká republika), M. LUKES (203 Česká republika), P. ROZNOVSKA (203 Česká republika), M. HOLA (203 Česká republika), J. FULNECKOVA (203 Česká republika), Jiří FAJKUS (203 Česká republika, garant, domácí) a K.J. ANGELIS (203 Česká republika)

Vydání

GENES, BASEL, MDPI AG, 2017, 2073-4425

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10603 Genetics and heredity

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.191

Kód RIV

RIV/00216224:14740/17:00095507

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.3390/genes8110331

UT WoS

000416800600041

Klíčová slova anglicky

Physcomitrella patens; Klebsormidium; Zygnema; DNA damage and repair; bleomycin; methyl methanesulfonate; ultraviolet light

Štítky

OA, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 2. 2018 15:46, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Research in algae usually focuses on the description and characterization of morphoand phenotype as a result of adaptation to a particular habitat and its conditions. To better understand the evolution of lineages we characterized responses of filamentous streptophyte green algae of the genera Klebsormidium and Zygnema, and of a land plantthe moss Physcomitrella patensto genotoxic stress that might be relevant to their environment. We studied the induction and repair of DNA double strand breaks (DSBs) elicited by the radiomimetic drug bleomycin, DNA single strand breaks (SSB) as consequence of base modification by the alkylation agent methyl methanesulfonate (MMS) and of ultra violet (UV)-induced photo-dimers, because the mode of action of these three genotoxic agents is well understood. We show that the Klebsormidium and Physcomitrella are similarly sensitive to introduced DNA lesions and have similar rates of DSBs repair. In contrast, less DNA damage and higher repair rate of DSBs was detected in Zygnema, suggesting different mechanisms of maintaining genome integrity in response to genotoxic stress. Nevertheless, contrary to fewer detected lesions is Zygnema more sensitive to genotoxic treatment than Klebsormidium and Physcomitrella

Návaznosti

GA16-01137S, projekt VaV

Název: Faktory genomové stability u mechu a vyšších rostlin

Investor: Grantová agentura ČR, Faktory genomové stability u mechu a vyšších rostlin

LQ1601, projekt VaV

Název: CEITEC 2020 (Akronym: CEITEC2020)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020

Citovat

VAGNEROVA, R., A. LUKESOVA, M. LUKES, P. ROZNOVSKA, M. HOLA, J. FULNECKOVA, Jiří FAJKUS a K.J. ANGELIS. Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress. GENES. BASEL: MDPI AG, 2017, roč. 8, č. 11, s. nestránkováno, 13 s. ISSN 2073-4425. Dostupné z: https://dx.doi.org/10.3390/genes8110331.

@article{1408645,
   author = {Vagnerova, R. and Lukesova, A. and Lukes, M. and Roznovska, P. and Hola, M. and Fulneckova, J. and Fajkus, Jiří and Angelis, K.J.},
   article_location = {BASEL},
   article_number = {11},
   doi = {http://dx.doi.org/10.3390/genes8110331},
   keywords = {Physcomitrella patens; Klebsormidium; Zygnema; DNA damage and repair; bleomycin; methyl methanesulfonate; ultraviolet light},
   language = {eng},
   issn = {2073-4425},
   journal = {GENES},
   title = {Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress},
   url = {http://www.mdpi.com/2073-4425/8/11/331},
   volume = {8},
   year = {2017}
}

TY  - JOUR
ID  - 1408645
AU  - Vagnerova, R. - Lukesova, A. - Lukes, M. - Roznovska, P. - Hola, M. - Fulneckova, J. - Fajkus, Jiří - Angelis, K.J.
PY  - 2017
TI  - Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress
JF  - GENES
VL  - 8
IS  - 11
SP  - nestránkováno
EP  - nestránkováno
PB  - MDPI AG
SN  - 20734425
KW  - Physcomitrella patens
KW  - Klebsormidium
KW  - Zygnema
KW  - DNA damage and repair
KW  - bleomycin
KW  - methyl methanesulfonate
KW  - ultraviolet light
UR  - http://www.mdpi.com/2073-4425/8/11/331
N2  - Research in algae usually focuses on the description and characterization of morphoand phenotype as a result of adaptation to a particular habitat and its conditions. To better understand the evolution of lineages we characterized responses of filamentous streptophyte green algae of the genera Klebsormidium and Zygnema, and of a land plantthe moss Physcomitrella patensto genotoxic stress that might be relevant to their environment. We studied the induction and repair of DNA double strand breaks (DSBs) elicited by the radiomimetic drug bleomycin, DNA single strand breaks (SSB) as consequence of base modification by the alkylation agent methyl methanesulfonate (MMS) and of ultra violet (UV)-induced photo-dimers, because the mode of action of these three genotoxic agents is well understood. We show that the Klebsormidium and Physcomitrella are similarly sensitive to introduced DNA lesions and have similar rates of DSBs repair. In contrast, less DNA damage and higher repair rate of DSBs was detected in Zygnema, suggesting different mechanisms of maintaining genome integrity in response to genotoxic stress. Nevertheless, contrary to fewer detected lesions is Zygnema more sensitive to genotoxic treatment than Klebsormidium and Physcomitrella
ER  -

VAGNEROVA, R., A. LUKESOVA, M. LUKES, P. ROZNOVSKA, M. HOLA, J. FULNECKOVA, Jiří FAJKUS a K.J. ANGELIS. Evolutionarily Distant Streptophyta Respond Differently to Genotoxic Stress. \textit{GENES}. BASEL: MDPI AG, 2017, roč.~8, č.~11, s.~nestránkováno, 13 s. ISSN~2073-4425. Dostupné z: https://dx.doi.org/10.3390/genes8110331.

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