Long-term time trends in human intake of POPs in the Czech
Republic indicate a need for continuous monitoring

J 2017

Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring

BÁNYIOVÁ, Katarína, Milena ČERNÁ, Ondřej MIKEŠ, Klára KOMPRDOVÁ, Anežka SHARMA et. al.

Základní údaje

Originální název

Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring

Autoři

BÁNYIOVÁ, Katarína (703 Slovensko, domácí), Milena ČERNÁ (203 Česká republika), Ondřej MIKEŠ (203 Česká republika, domácí), Klára KOMPRDOVÁ (203 Česká republika, domácí), Anežka SHARMA (203 Česká republika, domácí), Tenzing GYALPO (756 Švýcarsko), Pavel ČUPR (203 Česká republika, garant, domácí) a Martin SCHERINGER (756 Švýcarsko, domácí)

Vydání

Environment International, OXFORD (ENGLAND), PERGAMON-ELSEVIER SCIENCE LTD, 2017, 0160-4120

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.297

Kód RIV

RIV/00216224:14310/17:00095510

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.envint.2017.07.008

UT WoS

000411604400001

Klíčová slova anglicky

Polychlorinated biphenyls; Organochlorine pesticides; Daily intake; Human biomonitoring; Toxicokinetic model; Dietary exposure

Štítky

NZ, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 4. 2018 14:06, Ing. Nicole Zrilić

Anotace

V originále

Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) from the group of persistent organic pollutants are detected in human tissues years or even decades after their ban. Exposure to PCBs and OCPs can pose risks to human health. In the present study, we calculated the daily intakes of PCBs and OCPs in the Czech population and investigated the long-term trends of human exposure to POPs. Data on POP concentrations from a 16-year period of breast-milk monitoring were used. A toxicokinetic model with consideration of compound-specific elimination half-lives was used to calculate the mothers' daily intake of PCBs and OCPs representing the intake of POPs by all exposure routes. The calculated intakes were compared with dietary intakes calculated by the Czech National Institute of Public Health. The comparison shows good agreement of both intake estimates with decreasing intake trends of POPs in the Czech population in the time period studied. However, several fluctuations with peaks of higher levels were observed in both datasets which are not typical for the period after the ban of use and production of POPs. The available evidence suggests that the increases in chemical concentrations might be caused by food contamination. The calculated intakes of compounds with longer elimination half-lives, such as higher-chlorinated PCBs, were higher in older mothers. This "memory effect" was already observed in other studies and indicates higher exposure in earlier life periods of the mother. Our results suggest that exposure to POPs is still relevant for the Czech population in the period after the ban of the use and production of POPs (post-ban period), especially via food ingestion, though the intake trends are decreasing. Possible food contamination by POPs in the post-ban period requires further assessment.

Návaznosti

CZ.02.1.01/0.0/0.0/16_013/0001761, interní kód MU

Název: RECETOX RI - OP VVV (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX RI - OP VVV, PO 1 Posilování kapacit pro kvalitní výzkum

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

GA14-27941S, projekt VaV

Název: Kinetika perkutánní penetrace optických izomerů filtrů ultrafialového záření, bromovaných retardérů hoření a polárních pesticidů při dermální expozici

Investor: Grantová agentura ČR, Kinetika perkutánní penetrace optických izomerů filtrů ultrafialového záření, bromovaných retardérů hoření a polárních pesticidů při dermální expozici

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

Citovat

BÁNYIOVÁ, Katarína, Milena ČERNÁ, Ondřej MIKEŠ, Klára KOMPRDOVÁ, Anežka SHARMA, Tenzing GYALPO, Pavel ČUPR a Martin SCHERINGER. Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring. Environment International. OXFORD (ENGLAND): PERGAMON-ELSEVIER SCIENCE LTD, 2017, roč. 108, November, s. 1-10. ISSN 0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2017.07.008.

@article{1408676,
   author = {Bányiová, Katarína and Černá, Milena and Mikeš, Ondřej and Komprdová, Klára and Sharma, Anežka and Gyalpo, Tenzing and Čupr, Pavel and Scheringer, Martin},
   article_location = {OXFORD (ENGLAND)},
   article_number = {November},
   doi = {http://dx.doi.org/10.1016/j.envint.2017.07.008},
   keywords = {Polychlorinated biphenyls; Organochlorine pesticides; Daily intake; Human biomonitoring; Toxicokinetic model; Dietary exposure},
   language = {eng},
   issn = {0160-4120},
   journal = {Environment International},
   title = {Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring},
   url = {https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub},
   volume = {108},
   year = {2017}
}

TY  - JOUR
ID  - 1408676
AU  - Bányiová, Katarína - Černá, Milena - Mikeš, Ondřej - Komprdová, Klára - Sharma, Anežka - Gyalpo, Tenzing - Čupr, Pavel - Scheringer, Martin
PY  - 2017
TI  - Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring
JF  - Environment International
VL  - 108
IS  - November
SP  - 1-10
EP  - 1-10
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 01604120
KW  - Polychlorinated biphenyls
KW  - Organochlorine pesticides
KW  - Daily intake
KW  - Human biomonitoring
KW  - Toxicokinetic model
KW  - Dietary exposure
UR  - https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub
N2  - Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) from the group of persistent organic pollutants are detected in human tissues years or even decades after their ban. Exposure to PCBs and OCPs can pose risks to human health. In the present study, we calculated the daily intakes of PCBs and OCPs in the Czech population and investigated the long-term trends of human exposure to POPs. Data on POP concentrations from a 16-year period of breast-milk monitoring were used. A toxicokinetic model with consideration of compound-specific elimination half-lives was used to calculate the mothers' daily intake of PCBs and OCPs representing the intake of POPs by all exposure routes. The calculated intakes were compared with dietary intakes calculated by the Czech National Institute of Public Health. The comparison shows good agreement of both intake estimates with decreasing intake trends of POPs in the Czech population in the time period studied. However, several fluctuations with peaks of higher levels were observed in both datasets which are not typical for the period after the ban of use and production of POPs. The available evidence suggests that the increases in chemical concentrations might be caused by food contamination. The calculated intakes of compounds with longer elimination half-lives, such as higher-chlorinated PCBs, were higher in older mothers. This "memory effect" was already observed in other studies and indicates higher exposure in earlier life periods of the mother. Our results suggest that exposure to POPs is still relevant for the Czech population in the period after the ban of the use and production of POPs (post-ban period), especially via food ingestion, though the intake trends are decreasing. Possible food contamination by POPs in the post-ban period requires further assessment.
ER  -

BÁNYIOVÁ, Katarína, Milena ČERNÁ, Ondřej MIKEŠ, Klára KOMPRDOVÁ, Anežka SHARMA, Tenzing GYALPO, Pavel ČUPR a Martin SCHERINGER. Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring. \textit{Environment International}. OXFORD (ENGLAND): PERGAMON-ELSEVIER SCIENCE LTD, 2017, roč.~108, November, s.~1-10. ISSN~0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2017.07.008.

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