KULKARNI, M., I. JUNKAR, Petr HUMPOLÍČEK, Z. CAPAKOVA, Katarzyna Anna RADASZKIEWICZ, N. MIKUSOVA, Jiří PACHERNÍK, Marián LEHOCKÝ, A. IGLIC, Markéta HANÁČKOVÁ a M. MOZETIC. Interaction of nanostructured TiO2 biointerfaces with stern cells and biofilm-forming bacteria. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. AMSTERDAM: ELSEVIER SCIENCE BV, 2017, roč. 77, August, s. 500-507. ISSN 0928-4931. Dostupné z: https://dx.doi.org/10.1016/j.msec.2017.03.174. |
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@article{1409695, author = {Kulkarni, M. and Junkar, I. and Humpolíček, Petr and Capakova, Z. and Radaszkiewicz, Katarzyna Anna and Mikusova, N. and Pacherník, Jiří and Lehocký, Marián and Iglic, A. and Hanáčková, Markéta and Mozetic, M.}, article_location = {AMSTERDAM}, article_number = {August}, doi = {http://dx.doi.org/10.1016/j.msec.2017.03.174}, keywords = {Nanotubes; Titanium; Biofilm; Stem cells; Surface morphology}, language = {eng}, issn = {0928-4931}, journal = {MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS}, title = {Interaction of nanostructured TiO2 biointerfaces with stern cells and biofilm-forming bacteria}, url = {https://www.sciencedirect.com/science/article/pii/S0928493116319348?via%3Dihub}, volume = {77}, year = {2017} }
TY - JOUR ID - 1409695 AU - Kulkarni, M. - Junkar, I. - Humpolíček, Petr - Capakova, Z. - Radaszkiewicz, Katarzyna Anna - Mikusova, N. - Pacherník, Jiří - Lehocký, Marián - Iglic, A. - Hanáčková, Markéta - Mozetic, M. PY - 2017 TI - Interaction of nanostructured TiO2 biointerfaces with stern cells and biofilm-forming bacteria JF - MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS VL - 77 IS - August SP - 500-507 EP - 500-507 PB - ELSEVIER SCIENCE BV SN - 09284931 KW - Nanotubes KW - Titanium KW - Biofilm KW - Stem cells KW - Surface morphology UR - https://www.sciencedirect.com/science/article/pii/S0928493116319348?via%3Dihub L2 - https://www.sciencedirect.com/science/article/pii/S0928493116319348?via%3Dihub N2 - Nanostructured TiO2 nanotubes (NTs) of diameters from 15 to 100 nm were fabricated by an electrochemical anodization process. Biofilm-positive strains of Bacillus cereus and Pseudomonas aeruginosa behaved similarly on all TiO2 NTs as well as on native titanium (Ti) foil. The adhesion and growth of mesenchymal stem cells (MSc), embryonic stem cells (ESc), and pure cardiomyocytes derived from ESc exhibited significant differences. MSc as well as ESc were, in contrast to cardiomyocytes, able to adhere, and grow on TiO2 NTs. A correlation between NTs diameter and cell behaviour was however observed in the case of MSc and ESc. MSc were not in a physiological state in the case of 100 nm TiO2 NTs, while ESc were not able to grow on 15 nm TiO2 NTs. It can be stated that these differences can be assigned to different diameters of the NTs but not to the chemistry of the surface. This is the first study describing the comprehensive behaviour of both eukaryotic and prokaryotic cells on TiO2 NTs. On the basis of obtained results, it can be concluded that new generation of medical devices providing selective cell behaviour can be fabricated by optimizing the nanoscale morphology of TiO2. (C) 2017 Elsevier B.V. All rights reserved. ER -
KULKARNI, M., I. JUNKAR, Petr HUMPOLÍČEK, Z. CAPAKOVA, Katarzyna Anna RADASZKIEWICZ, N. MIKUSOVA, Jiří PACHERNÍK, Marián LEHOCKÝ, A. IGLIC, Markéta HANÁČKOVÁ a M. MOZETIC. Interaction of nanostructured TiO2 biointerfaces with stern cells and biofilm-forming bacteria. \textit{MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS}. AMSTERDAM: ELSEVIER SCIENCE BV, 2017, roč.~77, August, s.~500-507. ISSN~0928-4931. Dostupné z: https://dx.doi.org/10.1016/j.msec.2017.03.174.
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