Legacy and alternative halogenated flame retardants in human
milk in Europe: Implications for children's health

J 2017

Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health

ČECHOVÁ, Eliška, Šimon VOJTA, Petr KUKUČKA, Anton KOČAN, Tomáš TRNOVEC et. al.

Základní údaje

Originální název

Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health

Autoři

ČECHOVÁ, Eliška (203 Česká republika, domácí), Šimon VOJTA (203 Česká republika, domácí), Petr KUKUČKA (203 Česká republika, domácí), Anton KOČAN (703 Slovensko, domácí), Tomáš TRNOVEC (703 Slovensko), Lubica MURINOVA PALKOVICOVA (703 Slovensko), Marijke DE COCK (528 Nizozemské království), Margot VAN DE BOR (528 Nizozemské království), Joakim ASKEVOLD (578 Norsko), Merete EGGESBO (578 Norsko) a Martin SCHERINGER (756 Švýcarsko, garant, domácí)

Vydání

Environment International, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2017, 0160-4120

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.297

Kód RIV

RIV/00216224:14310/17:00100156

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.envint.2017.08.008

UT WoS

000411604400014

Klíčová slova anglicky

Alternative flame retardants; Developmental neurotoxicants; Human milk; Infant exposure; Polybrominated diphenyl ethers

Štítky

NZ, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 4. 2018 12:56, Ing. Nicole Zrilić

Anotace

V originále

In this study, 10 polybrominated diphenyl ethers (PBDEs) and 19 alternative halogenated flame retardants (AFRs) were determined in >450 human milk samples across three European countries, representing northern, western and eastern Europe. This study provides first insights into the occurrence of selected AFRs in mother milk samples and compares them among three European countries. Sums of median concentrations of the most frequently detected PBDEs were 2.16, 0.88 and 0.45 ng g(-1) lipid weight (lw) in Norway, the Netherlands and Slovakia, respectively. The sum of the concentrations of AFRs ranged from 0.14 to 0.25 ng g(-1) lw in all countries, which was 2 to 15 times less compared to S7PBDEs. The Penta-BDE replacement, bis(2-ethylhexyl) tetrabromophthalate, BEH-TEBP, was present at the greatest concentrations of any of the AFRs and in some samples exceeded concentrations of BDE 47 and BDE 153. Four AFRs including bromobenzenes (hexabromobenzene, pentabromobenzene, pentabromotoluene) and another Penta-BDE replacement (2-ethylhexyl-2,3,4,5-tetrabromobenzoate, EH-TBB) were detected in >42% of all human milk samples. Because of the potential developmental neurotoxicity of the halogenated flame retardants, infant dietary intakes via breastfeeding were estimated; in four cases the intakes of BDE 47 exceeded the reference dose indicating that the present concentrations may pose a risk for children.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

282957, interní kód MU

Název: DENAMIC - Developmental neurotoxicity assessment of mixtures in children (Akronym: DENAMIC)

Investor: Evropská unie, DENAMIC - Developmental neurotoxicity assessment of mixtures in children, Spolupráce

Citovat

ČECHOVÁ, Eliška, Šimon VOJTA, Petr KUKUČKA, Anton KOČAN, Tomáš TRNOVEC, Lubica MURINOVA PALKOVICOVA, Marijke DE COCK, Margot VAN DE BOR, Joakim ASKEVOLD, Merete EGGESBO a Martin SCHERINGER. Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health. Environment International. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2017, roč. 108, November, s. 137-145. ISSN 0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2017.08.008.

@article{1409698,
   author = {Čechová, Eliška and Vojta, Šimon and Kukučka, Petr and Kočan, Anton and Trnovec, Tomáš and Murinova Palkovicova, Lubica and de Cock, Marijke and van de Bor, Margot and Askevold, Joakim and Eggesbo, Merete and Scheringer, Martin},
   article_location = {OXFORD},
   article_number = {November},
   doi = {http://dx.doi.org/10.1016/j.envint.2017.08.008},
   keywords = {Alternative flame retardants; Developmental neurotoxicants; Human milk; Infant exposure; Polybrominated diphenyl ethers},
   language = {eng},
   issn = {0160-4120},
   journal = {Environment International},
   title = {Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health},
   url = {https://www.sciencedirect.com/science/article/pii/S0160412017306918?via%3Dihub},
   volume = {108},
   year = {2017}
}

TY  - JOUR
ID  - 1409698
AU  - Čechová, Eliška - Vojta, Šimon - Kukučka, Petr - Kočan, Anton - Trnovec, Tomáš - Murinova Palkovicova, Lubica - de Cock, Marijke - van de Bor, Margot - Askevold, Joakim - Eggesbo, Merete - Scheringer, Martin
PY  - 2017
TI  - Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health
JF  - Environment International
VL  - 108
IS  - November
SP  - 137-145
EP  - 137-145
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 01604120
KW  - Alternative flame retardants
KW  - Developmental neurotoxicants
KW  - Human milk
KW  - Infant exposure
KW  - Polybrominated diphenyl ethers
UR  - https://www.sciencedirect.com/science/article/pii/S0160412017306918?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0160412017306918?via%3Dihub
N2  - In this study, 10 polybrominated diphenyl ethers (PBDEs) and 19 alternative halogenated flame retardants (AFRs) were determined in >450 human milk samples across three European countries, representing northern, western and eastern Europe. This study provides first insights into the occurrence of selected AFRs in mother milk samples and compares them among three European countries. Sums of median concentrations of the most frequently detected PBDEs were 2.16, 0.88 and 0.45 ng g(-1) lipid weight (lw) in Norway, the Netherlands and Slovakia, respectively. The sum of the concentrations of AFRs ranged from 0.14 to 0.25 ng g(-1) lw in all countries, which was 2 to 15 times less compared to S7PBDEs. The Penta-BDE replacement, bis(2-ethylhexyl) tetrabromophthalate, BEH-TEBP, was present at the greatest concentrations of any of the AFRs and in some samples exceeded concentrations of BDE 47 and BDE 153. Four AFRs including bromobenzenes (hexabromobenzene, pentabromobenzene, pentabromotoluene) and another Penta-BDE replacement (2-ethylhexyl-2,3,4,5-tetrabromobenzoate, EH-TBB) were detected in >42% of all human milk samples. Because of the potential developmental neurotoxicity of the halogenated flame retardants, infant dietary intakes via breastfeeding were estimated; in four cases the intakes of BDE 47 exceeded the reference dose indicating that the present concentrations may pose a risk for children.
ER  -

ČECHOVÁ, Eliška, Šimon VOJTA, Petr KUKUČKA, Anton KOČAN, Tomáš TRNOVEC, Lubica MURINOVA PALKOVICOVA, Marijke DE COCK, Margot VAN DE BOR, Joakim ASKEVOLD, Merete EGGESBO a Martin SCHERINGER. Legacy and alternative halogenated flame retardants in human milk in Europe: Implications for children's health. \textit{Environment International}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2017, roč.~108, November, s.~137-145. ISSN~0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2017.08.008.

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