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@article{1410024, author = {Štěpaníková, Irena and Oates, Gabriela R. and Bateman, Lori Brand}, article_location = {ABINGDON, England}, article_number = {2}, doi = {http://dx.doi.org/10.1080/13557858.2016.1235681}, keywords = {Inflammation; body mass index; waist circumference; race/ethnicity; gender}, language = {eng}, issn = {1355-7858}, journal = {ETHNICITY AND HEALTH}, title = {Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender}, url = {https://www.tandfonline.com/doi/abs/10.1080/13557858.2016.1235681?journalCode=ceth20}, volume = {22}, year = {2017} }
TY - JOUR ID - 1410024 AU - Štěpaníková, Irena - Oates, Gabriela R. - Bateman, Lori Brand PY - 2017 TI - Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender JF - ETHNICITY AND HEALTH VL - 22 IS - 2 SP - 169-183 EP - 169-183 PB - ROUTLEDGE JOURNALS, TAYLOR and FRANCIS LTD SN - 13557858 KW - Inflammation KW - body mass index KW - waist circumference KW - race/ethnicity KW - gender UR - https://www.tandfonline.com/doi/abs/10.1080/13557858.2016.1235681?journalCode=ceth20 L2 - https://www.tandfonline.com/doi/abs/10.1080/13557858.2016.1235681?journalCode=ceth20 N2 - Objective: This study investigates the associations of body mass index (BMI) and waist circumference (WC) with markers of systemic inflammation in midlife by race and gender. Design: Data were obtained from the Survey of Midlife in the United States, a cross-sectional, observational study of Americans 35 years old or older (White men: N = 410; White women: N = 490; Black men: N = 58; Black women: N = 117). Inflammation was measured by concentrations of fibrinogen and C-reactive protein (CRP) in fasting plasma and concentrations of E-selectin and interleukin-6 (IL-6) in fasting serum. Anthropometric data were used to obtain BMI and WC. Socio-demographic and health-related factors were assessed with a survey. Multivariate models by race and gender were estimated to test the roles of BMI and WC for each inflammation marker. Results: Compared to White men, Black women have higher BMI and higher levels of all four inflammation markers; White women have lower BMI, lower WC, and lower E-selectin and fibrinogen but higher CRP; and Black men have higher fibrinogen. After adjusting for socio-demographic and health-related covariates as well as perceived discrimination, WC is associated with all four markers of inflammation among White men and women; with three markers (fibrinogen, CRP, and IL-6) of inflammation among Black women; and with CRP (and marginally with fibrinogen and E-selectin) among Black men. BMI is associated with higher CRP and fibrinogen among Black men (marginally so for White men) but not for women of either race. Conclusions: WC shows more consistent associations with inflammation markers than BMI, although the relationships vary by inflammation marker and population group. Our findings suggest that WC is a risk factor for systemic inflammation among White and Black men and women, and BMI is an additional risk factor for Black men. ER -
ŠTĚPANÍKOVÁ, Irena, Gabriela R. OATES a Lori Brand BATEMAN. Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender. \textit{ETHNICITY AND HEALTH}. ABINGDON, England: ROUTLEDGE JOURNALS, TAYLOR and FRANCIS LTD, 2017, roč.~22, č.~2, s.~169-183. ISSN~1355-7858. Dostupné z: https://dx.doi.org/10.1080/13557858.2016.1235681.
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