J 2017

Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender

ŠTĚPANÍKOVÁ, Irena, Gabriela R. OATES a Lori Brand BATEMAN

Základní údaje

Originální název

Does one size fit all? The role of body mass index and waist circumference in systemic inflammation in midlife by race and gender

Autoři

ŠTĚPANÍKOVÁ, Irena (203 Česká republika, garant, domácí), Gabriela R. OATES (840 Spojené státy) a Lori Brand BATEMAN (840 Spojené státy)

Vydání

ETHNICITY AND HEALTH, ABINGDON, England, ROUTLEDGE JOURNALS, TAYLOR and FRANCIS LTD, 2017, 1355-7858

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

50404 Antropology, ethnology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.766

Kód RIV

RIV/00216224:14310/17:00100198

Organizační jednotka

Přírodovědecká fakulta

DOI

UT WoS

000394520900006

Klíčová slova anglicky

Inflammation; body mass index; waist circumference; race/ethnicity; gender

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 3. 4. 2018 11:38, Ing. Nicole Zrilić

Anotace

V originále

Objective: This study investigates the associations of body mass index (BMI) and waist circumference (WC) with markers of systemic inflammation in midlife by race and gender. Design: Data were obtained from the Survey of Midlife in the United States, a cross-sectional, observational study of Americans 35 years old or older (White men: N = 410; White women: N = 490; Black men: N = 58; Black women: N = 117). Inflammation was measured by concentrations of fibrinogen and C-reactive protein (CRP) in fasting plasma and concentrations of E-selectin and interleukin-6 (IL-6) in fasting serum. Anthropometric data were used to obtain BMI and WC. Socio-demographic and health-related factors were assessed with a survey. Multivariate models by race and gender were estimated to test the roles of BMI and WC for each inflammation marker. Results: Compared to White men, Black women have higher BMI and higher levels of all four inflammation markers; White women have lower BMI, lower WC, and lower E-selectin and fibrinogen but higher CRP; and Black men have higher fibrinogen. After adjusting for socio-demographic and health-related covariates as well as perceived discrimination, WC is associated with all four markers of inflammation among White men and women; with three markers (fibrinogen, CRP, and IL-6) of inflammation among Black women; and with CRP (and marginally with fibrinogen and E-selectin) among Black men. BMI is associated with higher CRP and fibrinogen among Black men (marginally so for White men) but not for women of either race. Conclusions: WC shows more consistent associations with inflammation markers than BMI, although the relationships vary by inflammation marker and population group. Our findings suggest that WC is a risk factor for systemic inflammation among White and Black men and women, and BMI is an additional risk factor for Black men.