2017
Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases
PILER, Pavel, Vít KANDRNAL a Luděk BLÁHAZákladní údaje
Originální název
Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases
Autoři
PILER, Pavel (203 Česká republika, domácí), Vít KANDRNAL (203 Česká republika, domácí) a Luděk BLÁHA (203 Česká republika, garant, domácí)
Vydání
Public Health, LONDON, W B SAUNDERS CO LTD, 2017, 0033-3506
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30304 Public and environmental health
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 1.441
Kód RIV
RIV/00216224:14310/17:00100221
Organizační jednotka
Přírodovědecká fakulta
UT WoS
000399629500022
Klíčová slova anglicky
European birth cohorts; Study design; Research outcomes; Non-communicable diseases
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 30. 3. 2018 22:40, Ing. Nicole Zrilić
Anotace
V originále
Objectives: The objective of this review paper was to stimulate collaborative discussions toward the development of a general concept of an open source protocol for a feasible and efficient longitudinal birth cohort study exploring non-communicable diseases (NCDs), their multifactorial etiology and relations between various risk factors. Study design: The present paper systematically reviews the design of existing birth cohorts in Europe containing environmental exposure data, and assesses a quantity and quality of their research outcomes as their potential to be an effective tool for studying non communicable diseases and their risk factors. Methods: European birth cohorts with more than 3000 participants have been included in the study. A total number of scientific papers published in the internationally recognized journals and their impact factors and citation records were evaluated for all cohorts as surrogates for their efficiency to contribute to NCDs understanding and thus their prevention. Results: The birth cohorts contributing most significantly to the NCD understanding shared common features: (i) study size between 10,000 and 15,000 mother-child pairs; (ii) repeated assessment of children from prenatal into adulthood; and (iii) availability of biological samples. Smaller cohorts and cohorts with a specific focus generated a lower number of publications; however, these often received considerably a higher number of citations. Conclusions: General cohort studies with 10,000-15,000 mother child pairs allow a broader context interpretation, publish a higher number of articles, and often lead to the formation of infrastructures for 'spin-off (nested) studies'.
Návaznosti
LM2015051, projekt VaV |
| ||
LO1214, projekt VaV |
| ||
MUNI/M/1075/2013, interní kód MU |
|