| BOŘILOVÁ LINHARTOVÁ, Petra, Tereza DEISSOVÁ, Kristína MUSILOVÁ, Lenka ŽÁČKOVÁ, Martina KUKLETOVÁ, Lubomír KUKLA a Lydie IZAKOVIČOVÁ HOLLÁ. Lack of association between ENAM gene polymorphism and dental caries in primary and permanent teeth in Czech children. Clinical Oral Investigations. Heidelberg: Springer Heidelberg, 2018, roč. 22, č. 4, s. 1873-1877. ISSN 1432-6981. Dostupné z: https://dx.doi.org/10.1007/s00784-017-2280-2. |
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@article{1416816,
author = {Bořilová Linhartová, Petra and Deissová, Tereza and Musilová, Kristína and Žáčková, Lenka and Kukletová, Martina and Kukla, Lubomír and Izakovičová Hollá, Lydie},
article_location = {Heidelberg},
article_number = {4},
doi = {http://dx.doi.org/10.1007/s00784-017-2280-2},
keywords = {enamelin; gene polymorphism;dental caries;case-control study;primary dentition; permanent dentition},
language = {eng},
issn = {1432-6981},
journal = {Clinical Oral Investigations},
title = {Lack of association between ENAM gene polymorphism and dental caries in primary and permanent teeth in Czech children},
volume = {22},
year = {2018}
}
TY - JOUR
ID - 1416816
AU - Bořilová Linhartová, Petra - Deissová, Tereza - Musilová, Kristína - Žáčková, Lenka - Kukletová, Martina - Kukla, Lubomír - Izakovičová Hollá, Lydie
PY - 2018
TI - Lack of association between ENAM gene polymorphism and dental caries in primary and permanent teeth in Czech children
JF - Clinical Oral Investigations
VL - 22
IS - 4
SP - 1873-1877
EP - 1873-1877
PB - Springer Heidelberg
SN - 14326981
KW - enamelin
KW - gene polymorphism;dental caries;case-control study;primary dentition
KW - permanent dentition
N2 - Objectives The enamelin gene (ENAM) polymorphism (rs12640848) was recently associated with dental caries in primary teeth in Polish children. The aims of the present study were to prove this association in primary dentition and to find a possible effect of this variant on caries development in permanent dentition in Czech children. Materials and methods This study comprised 905 Czech children. Totally, 187 children aged 2-6 years with primary dentition [78 healthy subjects (with decayed/missing/filled teeth, dmft = 0) and 109 patients with early childhood caries (ECC; dmft >= 1)] were included in this case-control study. In addition, 177 subjects aged 13-15 years without caries (DMFT = 0) and 541 children with dental caries (DMFT >= 1) in permanent dentition were selected from the ELSPAC study. Genotype determination of the ENAM polymorphism (rs12640848) was based on the TaqMan method. Results No significant differences in the allele or genotype frequencies between the caries-free children and those affected by dental caries were observed in both primary and permanent dentitions. Conclusions Lack of association between the ENAM polymorphism (rs12640848) and dental caries in Czech children was detected.
ER -
BOŘILOVÁ LINHARTOVÁ, Petra, Tereza DEISSOVÁ, Kristína MUSILOVÁ, Lenka ŽÁČKOVÁ, Martina KUKLETOVÁ, Lubomír KUKLA a Lydie IZAKOVIČOVÁ HOLLÁ. Lack of association between ENAM gene polymorphism and dental caries in primary and permanent teeth in Czech children. \textit{Clinical Oral Investigations}. Heidelberg: Springer Heidelberg, 2018, roč.~22, č.~4, s.~1873-1877. ISSN~1432-6981. Dostupné z: https://dx.doi.org/10.1007/s00784-017-2280-2.
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