Comparison of the Copenhagen Index versus ROMA for the
preoperative assessment of women with ovarian tumors

J 2018

Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

MINÁŘ, Luboš, Michal FELSINGER, Zdeňka ČERMÁKOVÁ, Filip ZLÁMAL, Julie BIENERTOVÁ VAŠKŮ et. al.

Základní údaje

Originální název

Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

Autoři

MINÁŘ, Luboš (203 Česká republika, garant, domácí), Michal FELSINGER (203 Česká republika, domácí), Zdeňka ČERMÁKOVÁ (203 Česká republika), Filip ZLÁMAL (203 Česká republika, domácí) a Julie BIENERTOVÁ VAŠKŮ (203 Česká republika, domácí)

Vydání

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, CLARE, ELSEVIER IRELAND LTD, 2018, 0020-7292

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.671

Kód RIV

RIV/00216224:14110/18:00102797

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1002/ijgo.12371

UT WoS

000419300300018

Klíčová slova anglicky

Cancer antigen 125; Copenhagen Index; Human epididymis protein 4; Ovarian tumor; Risk of Ovarian Malignancy Algorithm

Štítky

14110411, 14110518, EL OK, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 3. 2019 10:37, Soňa Böhmová

Anotace

V originále

Objective To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. Methods In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. Results Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. Conclusion CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

Citovat

MINÁŘ, Luboš, Michal FELSINGER, Zdeňka ČERMÁKOVÁ, Filip ZLÁMAL a Julie BIENERTOVÁ VAŠKŮ. Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. CLARE: ELSEVIER IRELAND LTD, 2018, roč. 140, č. 2, s. 241-246. ISSN 0020-7292. Dostupné z: https://dx.doi.org/10.1002/ijgo.12371.

@article{1418456,
   author = {Minář, Luboš and Felsinger, Michal and Čermáková, Zdeňka and Zlámal, Filip and Bienertová Vašků, Julie},
   article_location = {CLARE},
   article_number = {2},
   doi = {http://dx.doi.org/10.1002/ijgo.12371},
   keywords = {Cancer antigen 125; Copenhagen Index; Human epididymis protein 4; Ovarian tumor; Risk of Ovarian Malignancy Algorithm},
   language = {eng},
   issn = {0020-7292},
   journal = {INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS},
   title = {Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors},
   volume = {140},
   year = {2018}
}

TY  - JOUR
ID  - 1418456
AU  - Minář, Luboš - Felsinger, Michal - Čermáková, Zdeňka - Zlámal, Filip - Bienertová Vašků, Julie
PY  - 2018
TI  - Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors
JF  - INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
VL  - 140
IS  - 2
SP  - 241-246
EP  - 241-246
PB  - ELSEVIER IRELAND LTD
SN  - 00207292
KW  - Cancer antigen 125
KW  - Copenhagen Index
KW  - Human epididymis protein 4
KW  - Ovarian tumor
KW  - Risk of Ovarian Malignancy Algorithm
N2  - Objective To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. Methods In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. Results Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. Conclusion CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.
ER  -

MINÁŘ, Luboš, Michal FELSINGER, Zdeňka ČERMÁKOVÁ, Filip ZLÁMAL a Julie BIENERTOVÁ VAŠKŮ. Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors. \textit{INTERNATIONAL JOURNAL OF GYNECOLOGY \&{}amp; OBSTETRICS}. CLARE: ELSEVIER IRELAND LTD, 2018, roč.~140, č.~2, s.~241-246. ISSN~0020-7292. Dostupné z: https://dx.doi.org/10.1002/ijgo.12371.

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