Trends in the treatment and outcomes of elderly patients with
acute coronary syndrome: Results from the CZECH registries

J 2018

Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

STAŠKOVÁ, Klára, Pavel TOUŠEK, František TOUŠEK, Anna MALÁ, Michael ŽELÍZKO et. al.

Základní údaje

Originální název

Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

Autoři

STAŠKOVÁ, Klára (203 Česká republika), Pavel TOUŠEK (203 Česká republika, garant), František TOUŠEK (203 Česká republika), Anna MALÁ (203 Česká republika), Michael ŽELÍZKO (203 Česká republika), David HORÁK (203 Česká republika), Martin SLUKA (203 Česká republika), Alexandra VODZINSKÁ (203 Česká republika), Radek JANČAR (203 Česká republika), Michael ASCHERMANN (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí) a Petr WIDIMSKÝ (203 Česká republika)

Vydání

Cor et Vasa, AMSTERDAM, ELSEVIER SCIENCE BV, 2018, 0010-8650

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/18:00102945

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.crvasa.2017.02.007

UT WoS

000426976600012

Klíčová slova anglicky

Elderly; Acute coronary syndrome; Treatment strategy; Outcome

Štítky

14119612, EL OK, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 2. 2019 15:44, Soňa Böhmová

Anotace

V originále

Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +/- 4 and 82.1 +/- 5 years (p < 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p < 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.

Citovat

STAŠKOVÁ, Klára, Pavel TOUŠEK, František TOUŠEK, Anna MALÁ, Michael ŽELÍZKO, David HORÁK, Martin SLUKA, Alexandra VODZINSKÁ, Radek JANČAR, Michael ASCHERMANN, Jiří JARKOVSKÝ a Petr WIDIMSKÝ. Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries. Cor et Vasa. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč. 60, č. 1, s. "E66"-"E69", 4 s. ISSN 0010-8650. Dostupné z: https://dx.doi.org/10.1016/j.crvasa.2017.02.007.

@article{1419904,
   author = {Stašková, Klára and Toušek, Pavel and Toušek, František and Malá, Anna and Želízko, Michael and Horák, David and Sluka, Martin and Vodzinská, Alexandra and Jančar, Radek and Aschermann, Michael and Jarkovský, Jiří and Widimský, Petr},
   article_location = {AMSTERDAM},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.crvasa.2017.02.007},
   keywords = {Elderly; Acute coronary syndrome; Treatment strategy; Outcome},
   language = {eng},
   issn = {0010-8650},
   journal = {Cor et Vasa},
   title = {Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries},
   volume = {60},
   year = {2018}
}

TY  - JOUR
ID  - 1419904
AU  - Stašková, Klára - Toušek, Pavel - Toušek, František - Malá, Anna - Želízko, Michael - Horák, David - Sluka, Martin - Vodzinská, Alexandra - Jančar, Radek - Aschermann, Michael - Jarkovský, Jiří - Widimský, Petr
PY  - 2018
TI  - Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries
JF  - Cor et Vasa
VL  - 60
IS  - 1
SP  - "E66"-"E69"
EP  - "E66"-"E69"
PB  - ELSEVIER SCIENCE BV
SN  - 00108650
KW  - Elderly
KW  - Acute coronary syndrome
KW  - Treatment strategy
KW  - Outcome
N2  - Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +/- 4 and 82.1 +/- 5 years (p < 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p < 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.
ER  -

STAŠKOVÁ, Klára, Pavel TOUŠEK, František TOUŠEK, Anna MALÁ, Michael ŽELÍZKO, David HORÁK, Martin SLUKA, Alexandra VODZINSKÁ, Radek JANČAR, Michael ASCHERMANN, Jiří JARKOVSKÝ a Petr WIDIMSKÝ. Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries. \textit{Cor et Vasa}. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč.~60, č.~1, s.~''E66''-''E69'', 4 s. ISSN~0010-8650. Dostupné z: https://dx.doi.org/10.1016/j.crvasa.2017.02.007.

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