J 2018

Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature

KUNOVSKÝ, Lumír, Zdeněk KALA, Roman SVATOŇ, Petr MORAVČÍK, Jan MAZANEC et. al.

Základní údaje

Originální název

Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature

Autoři

KUNOVSKÝ, Lumír (203 Česká republika, garant, domácí), Zdeněk KALA (203 Česká republika, domácí), Roman SVATOŇ (703 Slovensko, domácí), Petr MORAVČÍK (203 Česká republika, domácí), Jan MAZANEC (203 Česká republika, domácí), Jakub HUSTÝ (203 Česká republika, domácí) a Vladimír PROCHÁZKA (203 Česká republika, domácí)

Vydání

Annals of hepatology, Mexico City, Ediciones Medicina y Cultura, 2018, 1665-2681

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30219 Gastroenterology and hepatology

Stát vydavatele

Mexiko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.895

Kód RIV

RIV/00216224:14110/18:00102959

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000460748500021

Klíčová slova anglicky

Biliary intraductal papillary mucinous neoplasm; Hepatic mucinous cystic neoplasm; Liver lesions; Ovarian-like stroma; Surgery

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 26. 4. 2019 09:19, Soňa Böhmová

Anotace

V originále

Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L. We present the case of a 33-year-old woman with a rapid progression of a cystic tumor of the liver. In 2 years, the lesion increased from 27 to 64 mm and a dilation of the left hepatic duct appeared. Percutaneous transhepatic drainage with a biopsy was performed. No malignant cells were found on biopsy. Because of the rapid progression of the cystic tumor and unclear malignant potential, left hemihepatectomy was performed. Even though tumor masses were present in the biliary duct, on the basis of the presence of OLS, histology finally confirmed MCN-L with intermediate-grade intraepithelial dysplasia to high-grade intraepithelial dysplasia. The patient is currently under oncologic follow-up with no signs of recurrence of the disease. We present a rare case where MCN-L caused a dilation of the left hepatic duct, a sign that is usually a characteristic of IPMN-B.