J 2018

Clinical value of different QRS-Tangle expressions

HNATKOVA, Katerina, Joachim SEEGERS, Petra BARTHEL, Tomáš NOVOTNÝ, Peter SMETANA et. al.

Základní údaje

Originální název

Clinical value of different QRS-Tangle expressions

Autoři

HNATKOVA, Katerina (826 Velká Británie a Severní Irsko), Joachim SEEGERS (276 Německo), Petra BARTHEL (276 Německo), Tomáš NOVOTNÝ (203 Česká republika, domácí), Peter SMETANA (40 Rakousko), Markus ZABEL (276 Německo), Georg SCHMIDT (276 Německo) a Marek MALIK (826 Velká Británie a Severní Irsko, garant)

Vydání

EP Europace, Oxford, Oxford University Press, 2018, 1099-5129

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.047

Kód RIV

RIV/00216224:14110/18:00103545

Organizační jednotka

Lékařská fakulta

UT WoS

000440944300017

Klíčová slova anglicky

QRS-T angle; Total cosine R to T; Reproducibility; Mortality risk prediction; Standardization

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 9. 2. 2019 21:37, Soňa Böhmová

Anotace

V originále

Aims Increased spatial angle between QRS complex and T wave loop orientations has repeatedly been shown to predict cardiac risk. However, there is no consensus on the methods for the calculation of the angle. This study compared the reproducibility and predictive power of three most common ways of QRS-T angle assessment. Methods and results Electrocardiograms of 352 healthy subjects, 941 survivors of acute myocardial infarction (MI), and 605 patients recorded prior to the implantation of automatic defibrillator [implantable cardioverter defibrillator (ICD)] were used to obtain QRS-T angle measurements by the maximum R to T (MRT), area R to T (ART), and total cosine R to T (TCRT) methods. The results were compared in terms of physiologic reproducibility and power to predict mortality in the cardiac patients during 5-year follow-up. Maximum R to T results were significantly less reproducible compared to the other two methods. Among both survivors of acute MI and ICD recipients, TCRT method was statistically significantly more powerful in predicting mortality during follow-up. Among the acute MI survivors, increased spatial QRS-T angle (TCRT assessment) was particularly powerful in predicting sudden cardiac death with the area under the receiver operator characteristic of 78% (90% confidence interval 63 90%). Among the ICD recipients, TCRT also predicted mortality significantly among patients with prolonged QRS complex duration when the spatial orientation of the QRS complex is poorly defined. Conclusion The TCRT method for the assessment of spatial QRS-T angle appears to offer important advantages in comparison to other methods of measurement. This approach should be included in future clinical studies of the QRS-T angle. The TCRT method might also be a reasonable candidate for the standardization of the QRS-T angle assessment.