STALLMACH, Andreas, Veli-Jukka ANTTILA, Markus HELL, Simon GWYNN, Paloma MERINO-AMADOR, Nicola PETROSILLO, Zdeněk RÁČIL, Tim WARREN, Christoph WENISCH a Mark WILCOX. Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals. ZEITSCHRIFT FUR GASTROENTEROLOGIE. STUTTGART: GEORG THIEME VERLAG KG, 2018, roč. 56, č. 7, s. 731-737. ISSN 0044-2771. Dostupné z: https://dx.doi.org/10.1055/s-0044-100045.
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Základní údaje
Originální název Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals
Autoři STALLMACH, Andreas (276 Německo), Veli-Jukka ANTTILA (246 Finsko), Markus HELL (40 Rakousko), Simon GWYNN (826 Velká Británie a Severní Irsko), Paloma MERINO-AMADOR (724 Španělsko), Nicola PETROSILLO (380 Itálie), Zdeněk RÁČIL (203 Česká republika, garant, domácí), Tim WARREN (826 Velká Británie a Severní Irsko), Christoph WENISCH (40 Rakousko) a Mark WILCOX (826 Velká Británie a Severní Irsko).
Vydání ZEITSCHRIFT FUR GASTROENTEROLOGIE, STUTTGART, GEORG THIEME VERLAG KG, 2018, 0044-2771.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30219 Gastroenterology and hepatology
Stát vydavatele Německo
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.236
Kód RIV RIV/00216224:14110/18:00103950
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1055/s-0044-100045
UT WoS 000437861800016
Klíčová slova anglicky inflammatory bowel disease; clostridium difficile infection; consensus report
Štítky 14110212, rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Soňa Böhmová, učo 232884. Změněno: 10. 2. 2019 14:51.
Anotace
Introduction In patients with inflammatory bowel disease (IBD), Clostridium difficile infection (CDI) is a risk factor for both morbidity and mortality. Currently, appropriate management is unclear. Guidance on best practice in the diagnosis and treatment of CDI in IBD patients is therefore needed. Methods A multidisciplinary group of clinicians involved in the treatment of patients with IBD and CDI developed 27 consensus statements. Respondents were asked to rate their agreement with each statement using a 4-point Likert scale. Amodified Delphi methodology was used to review responses of 442 physicians from different specialties (including infectious disease specialists [n = 104], microbiologists [n = 95], and gastroenterologists [n = 73]). A threshold of 75 % agreement was predefined as consensus. Results Consensus was achieved for 17 of the 27 statements. Unprompted recognition of risk factors for CDI was low. Intensification of immunosuppressive therapy in the absence of clinical improvement was controversial. Clear definitions of treatment failure of antibiotic therapy in CDI and recurrence of CDI in IBD are needed. Respondents require further clarity regarding the place of fecal microbiota transplantation in CDI patients with IBD. Differences were observed between the perceptions of microbiologists and gastroenterologists, as well as between countries. Conclusions Different perceptions both between specialties and geographical locations complicate the development of an internationally accepted algorithm for the diagnosis and treatment of CDI in patients with IBD. This study highlights the need for future studies in this area.
VytisknoutZobrazeno: 10. 5. 2024 13:46