Inflammatory bowel disease and Clostridium difficile infection:
contrasting views of international clinical professionals

J 2018

Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals

STALLMACH, Andreas, Veli-Jukka ANTTILA, Markus HELL, Simon GWYNN, Paloma MERINO-AMADOR et. al.

Základní údaje

Originální název

Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals

Autoři

STALLMACH, Andreas (276 Německo), Veli-Jukka ANTTILA (246 Finsko), Markus HELL (40 Rakousko), Simon GWYNN (826 Velká Británie a Severní Irsko), Paloma MERINO-AMADOR (724 Španělsko), Nicola PETROSILLO (380 Itálie), Zdeněk RÁČIL (203 Česká republika, garant, domácí), Tim WARREN (826 Velká Británie a Severní Irsko), Christoph WENISCH (40 Rakousko) a Mark WILCOX (826 Velká Británie a Severní Irsko)

Vydání

ZEITSCHRIFT FUR GASTROENTEROLOGIE, STUTTGART, GEORG THIEME VERLAG KG, 2018, 0044-2771

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30219 Gastroenterology and hepatology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.236

Kód RIV

RIV/00216224:14110/18:00103950

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1055/s-0044-100045

UT WoS

000437861800016

Klíčová slova anglicky

inflammatory bowel disease; clostridium difficile infection; consensus report

Štítky

14110212, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 2. 2019 14:51, Soňa Böhmová

Anotace

V originále

Introduction In patients with inflammatory bowel disease (IBD), Clostridium difficile infection (CDI) is a risk factor for both morbidity and mortality. Currently, appropriate management is unclear. Guidance on best practice in the diagnosis and treatment of CDI in IBD patients is therefore needed. Methods A multidisciplinary group of clinicians involved in the treatment of patients with IBD and CDI developed 27 consensus statements. Respondents were asked to rate their agreement with each statement using a 4-point Likert scale. Amodified Delphi methodology was used to review responses of 442 physicians from different specialties (including infectious disease specialists [n = 104], microbiologists [n = 95], and gastroenterologists [n = 73]). A threshold of 75 % agreement was predefined as consensus. Results Consensus was achieved for 17 of the 27 statements. Unprompted recognition of risk factors for CDI was low. Intensification of immunosuppressive therapy in the absence of clinical improvement was controversial. Clear definitions of treatment failure of antibiotic therapy in CDI and recurrence of CDI in IBD are needed. Respondents require further clarity regarding the place of fecal microbiota transplantation in CDI patients with IBD. Differences were observed between the perceptions of microbiologists and gastroenterologists, as well as between countries. Conclusions Different perceptions both between specialties and geographical locations complicate the development of an internationally accepted algorithm for the diagnosis and treatment of CDI in patients with IBD. This study highlights the need for future studies in this area.

Citovat

STALLMACH, Andreas, Veli-Jukka ANTTILA, Markus HELL, Simon GWYNN, Paloma MERINO-AMADOR, Nicola PETROSILLO, Zdeněk RÁČIL, Tim WARREN, Christoph WENISCH a Mark WILCOX. Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals. ZEITSCHRIFT FUR GASTROENTEROLOGIE. STUTTGART: GEORG THIEME VERLAG KG, 2018, roč. 56, č. 7, s. 731-737. ISSN 0044-2771. Dostupné z: https://dx.doi.org/10.1055/s-0044-100045.

@article{1446056,
   author = {Stallmach, Andreas and Anttila, VeliandJukka and Hell, Markus and Gwynn, Simon and MerinoandAmador, Paloma and Petrosillo, Nicola and Ráčil, Zdeněk and Warren, Tim and Wenisch, Christoph and Wilcox, Mark},
   article_location = {STUTTGART},
   article_number = {7},
   doi = {http://dx.doi.org/10.1055/s-0044-100045},
   keywords = {inflammatory bowel disease; clostridium difficile infection; consensus report},
   language = {eng},
   issn = {0044-2771},
   journal = {ZEITSCHRIFT FUR GASTROENTEROLOGIE},
   title = {Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals},
   volume = {56},
   year = {2018}
}

TY  - JOUR
ID  - 1446056
AU  - Stallmach, Andreas - Anttila, Veli-Jukka - Hell, Markus - Gwynn, Simon - Merino-Amador, Paloma - Petrosillo, Nicola - Ráčil, Zdeněk - Warren, Tim - Wenisch, Christoph - Wilcox, Mark
PY  - 2018
TI  - Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals
JF  - ZEITSCHRIFT FUR GASTROENTEROLOGIE
VL  - 56
IS  - 7
SP  - 731-737
EP  - 731-737
PB  - GEORG THIEME VERLAG KG
SN  - 00442771
KW  - inflammatory bowel disease
KW  - clostridium difficile infection
KW  - consensus report
N2  - Introduction In patients with inflammatory bowel disease (IBD), Clostridium difficile infection (CDI) is a risk factor for both morbidity and mortality. Currently, appropriate management is unclear. Guidance on best practice in the diagnosis and treatment of CDI in IBD patients is therefore needed. Methods A multidisciplinary group of clinicians involved in the treatment of patients with IBD and CDI developed 27 consensus statements. Respondents were asked to rate their agreement with each statement using a 4-point Likert scale. Amodified Delphi methodology was used to review responses of 442 physicians from different specialties (including infectious disease specialists [n = 104], microbiologists [n = 95], and gastroenterologists [n = 73]). A threshold of 75 % agreement was predefined as consensus. Results Consensus was achieved for 17 of the 27 statements. Unprompted recognition of risk factors for CDI was low. Intensification of immunosuppressive therapy in the absence of clinical improvement was controversial. Clear definitions of treatment failure of antibiotic therapy in CDI and recurrence of CDI in IBD are needed. Respondents require further clarity regarding the place of fecal microbiota transplantation in CDI patients with IBD. Differences were observed between the perceptions of microbiologists and gastroenterologists, as well as between countries. Conclusions Different perceptions both between specialties and geographical locations complicate the development of an internationally accepted algorithm for the diagnosis and treatment of CDI in patients with IBD. This study highlights the need for future studies in this area.
ER  -

STALLMACH, Andreas, Veli-Jukka ANTTILA, Markus HELL, Simon GWYNN, Paloma MERINO-AMADOR, Nicola PETROSILLO, Zdeněk RÁČIL, Tim WARREN, Christoph WENISCH a Mark WILCOX. Inflammatory bowel disease and Clostridium difficile infection: contrasting views of international clinical professionals. \textit{ZEITSCHRIFT FUR GASTROENTEROLOGIE}. STUTTGART: GEORG THIEME VERLAG KG, 2018, roč.~56, č.~7, s.~731-737. ISSN~0044-2771. Dostupné z: https://dx.doi.org/10.1055/s-0044-100045.

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