Kardiovize Brno 2030, a prospective cardiovascular health study in Central Europe: Methods, baseline findings and future directions

MOVSISYAN, Narine K., Manlio VINCIGUERRA, Francisco LOPEZ-JIMENEZ, Šárka KUNZOVÁ, Martin HOMOLKA, Jana JARESOVA, Renata CIFKOVA and Odnřej SOCHOR. Kardiovize Brno 2030, a prospective cardiovascular health study in Central Europe: Methods, baseline findings and future directions. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. LONDON: SAGE PUBLICATIONS LTD, 2018, vol. 25, No 1, p. 54-64. ISSN 2047-4873. Available from: https://dx.doi.org/10.1177/2047487317726623.

Basic information

• Original name: Kardiovize Brno 2030, a prospective cardiovascular health study in Central Europe: Methods, baseline findings and future directions
• Authors: MOVSISYAN, Narine K. (203 Czech Republic, guarantor), Manlio VINCIGUERRA (203 Czech Republic), Francisco LOPEZ-JIMENEZ (840 United States of America), Šárka KUNZOVÁ (203 Czech Republic, belonging to the institution), Martin HOMOLKA (203 Czech Republic), Jana JARESOVA (203 Czech Republic), Renata CIFKOVA (203 Czech Republic) and Odnřej SOCHOR (203 Czech Republic).
• Edition: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, LONDON, SAGE PUBLICATIONS LTD, 2018, 2047-4873.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30201 Cardiac and Cardiovascular systems
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 5.640
• RIV identification code: RIV/00216224:14110/18:00103956
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1177/2047487317726623
• UT WoS: 000417694900009
• Keywords in English: Prospective cohort study; cardiovascular risk factors; urban population; Central and Eastern Europe
• Tags: 14110525, rivok
• Tags: International impact, Reviewed

Abstract

Background Atherosclerotic cardiovascular disease is highly prevalent in Eastern and Central Europe, where the incidence is the highest in the world. The Kardiovize Brno 2030 study was designed as a prospective cohort study to investigate the complex relationships of cardiovascular disease and outcomes with a range of biological, psychosocial, environmental, behavioral, and economic factors in an urban population of the Czech Republic. Methods We randomly selected a 1% sample of the city of Brno residents aged 25-64 years stratified by sex and age. The study assessed traditional and novel cardiovascular disease risk factors, including sociodemographic and smoking status, physical activity, diet, depression, stress, body fat, cardio-ankle vascular index, and intima media thickness, complemented by blood tests; biological samples were stored for future analyses. Results The study enrolled 2160 participants (54.8% women), with a mean age of 4711.3 years. They were mostly full-time employed (75.6%) and married (62.1%). Hyperlipidemia was highly prevalent (70.7% in men, and 67.1% in women, NS). Hypertension and diabetes mellitus were more prevalent in men than in women (54.3% vs. 38.7% and 7.1% vs. 3.5%, respectively, P<0.001 for both). A total of 25.3% of men and 21.9% of women smoked, whereas 20.0% and 43.0% of men and 18.1% and 26.6% of women were obese and overweight, respectively. Conclusions Cardiovascular risk factors are highly prevalent in the city of Brno, an urban population from Central Europe. The Kardiovize Brno 2030 study will provide unique multidimensional and longitudinal cardiovascular health data from a region where epidemiological studies are scarce.