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@article{1449697, author = {Pleva, Leos and Kukla, Pavel and Hlinomaz, Ota}, article_location = {Beijing}, article_number = {2}, doi = {http://dx.doi.org/10.11909/j.issn.1671-5411.2018.02.007}, keywords = {Drug-eluting balloon; Drug-eluting stent; In-stent restenosis}, language = {eng}, issn = {1671-5411}, journal = {Journal of Geriatric Cardiology}, title = {Treatment of coronary in-stent restenosis: a systematic review}, volume = {15}, year = {2018} }
TY - JOUR ID - 1449697 AU - Pleva, Leos - Kukla, Pavel - Hlinomaz, Ota PY - 2018 TI - Treatment of coronary in-stent restenosis: a systematic review JF - Journal of Geriatric Cardiology VL - 15 IS - 2 SP - 173-184 EP - 173-184 PB - Science Press SN - 16715411 KW - Drug-eluting balloon KW - Drug-eluting stent KW - In-stent restenosis N2 - Coronary stent implantation has significantly improved percutaneous coronary intervention and enabled the management of early complications of plain balloon angioplasty. However, a new complication has accompanied these improvements: in-stent restenosis (ISR) arising from neointimal hyperplasia. ISR after coronary angioplasty is currently one of the main limitations of this method, leading to the recurrence of exertional angina pectoris or acute coronary syndromes. The clinical incidence of ISR after bare-metal stent (BMS) implantation is approximately 20%-35%. The use of drug-eluting stents (DES) has led to a further decrease in the occurrence of ISR to 5%-10%. Evidence resulting from controlled clinical studies suggests that DES and drug-eluting balloon catheters (DEB) provide the best clinical and angiographic results in the treatment of ISR. We undertook a systematic review of the pathophysiology, diagnostics and treatment options for BMS- and DES-ISR. We discuss recent randomised studies, comparing different DES or DEB used for BMS or DES-ISR treatment, as well as the use of new biovascular scafolds and the topic of scafold restenosis. ER -
PLEVA, Leos, Pavel KUKLA a Ota HLINOMAZ. Treatment of coronary in-stent restenosis: a systematic review. \textit{Journal of Geriatric Cardiology}. Beijing: Science Press, 2018, roč.~15, č.~2, s.~173-184. ISSN~1671-5411. Dostupné z: https://dx.doi.org/10.11909/j.issn.1671-5411.2018.02.007.
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