Cardiac resynchronization therapy - A comparison of VV delay
optimization by 3D echocardiography using systolic dyssynchrony
index and QRS width assessment at 6 months after CRT
implantation

J 2018

Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ, Petr VOJTISEK et. al.

Základní údaje

Originální název

Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation

Autoři

VONDRAK, Jiri (203 Česká republika, garant), Dan MAREK (203 Česká republika), Jan VECERA (203 Česká republika), Klára BENEŠOVÁ (203 Česká republika, domácí) a Petr VOJTISEK (203 Česká republika)

Vydání

cor et Vasa, AMSTERDAM, ELSEVIER SCIENCE BV, 2018, 0010-8650

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/18:00104186

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.crvasa.2017.11.006

UT WoS

000442902500005

Klíčová slova anglicky

3D echocardiography; Dyssynchrony; Cardiac resynchronization therapy; Optimization; Systolic dyssynchrony index; Clinical outcome; Volumetric responders

Štítky

14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 2. 2019 21:15, Soňa Böhmová

Anotace

V originále

Aim: The aim of this study was to compare the setting of interventricular (VV) delay by 3D echocardiography (3DE) using systolic dyssynchrony index (SDI) versus QRS width measurement in new cardiac resynchronization therapy (CRT) recipients. We observed the impact on the reduction of left ventricle volumes and increase in volumetric responders (defined as a = 15% reduction in left ventricular end-systolic volume (LVESv)) at the 6-month follow-up. Methods: We included 63 patients with recently implanted CRT in this open-label, randomized trial. Patients were randomized into two groups. VV delay was set by the QRS width in the group 1 (n 31) to obtain the narrowest QRS complex and by SDI in the group 2 (n 32) to achieve the lowest possible value. We evaluated LVESv, left ventricular ejection fraction (LVEF) by 3DE, before CRT implantation and at 6-month follow-up, in all patients. We also obtained clinical parameters and the level of NT-proBNP. Results: The second group showed only a trend toward greater reduction of LVESv (-33 +/- 55 ml vs. -48 +/- 43 ml; P 0.367), increase in LVEF (+ 7.3 +/- 10.9% vs. + 10.2 +/- 9.4%; P 0.210) and greater number of volumetric responders (14 vs. 18; P 0.612) compared with the group 1 at 6-month follow-up. There were also no significant differences in clinical outcomes and the level of NT-proBNP. Conclusion: Individual CRT optimization using SDI compared with QRS duration assessment did not reveal any significant differences in echocardiographic parameters and clinical outcomes at 6-month follow-up. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.

Citovat

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ a Petr VOJTISEK. Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation. cor et Vasa. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč. 60, č. 4, s. "E367"-"E376", 10 s. ISSN 0010-8650. Dostupné z: https://dx.doi.org/10.1016/j.crvasa.2017.11.006.

@article{1455096,
   author = {Vondrak, Jiri and Marek, Dan and Vecera, Jan and Benešová, Klára and Vojtisek, Petr},
   article_location = {AMSTERDAM},
   article_number = {4},
   doi = {http://dx.doi.org/10.1016/j.crvasa.2017.11.006},
   keywords = {3D echocardiography; Dyssynchrony; Cardiac resynchronization therapy; Optimization; Systolic dyssynchrony index; Clinical outcome; Volumetric responders},
   language = {eng},
   issn = {0010-8650},
   journal = {cor et Vasa},
   title = {Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation},
   volume = {60},
   year = {2018}
}

TY  - JOUR
ID  - 1455096
AU  - Vondrak, Jiri - Marek, Dan - Vecera, Jan - Benešová, Klára - Vojtisek, Petr
PY  - 2018
TI  - Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
JF  - cor et Vasa
VL  - 60
IS  - 4
SP  - "E367"-"E376"
EP  - "E367"-"E376"
PB  - ELSEVIER SCIENCE BV
SN  - 00108650
KW  - 3D echocardiography
KW  - Dyssynchrony
KW  - Cardiac resynchronization therapy
KW  - Optimization
KW  - Systolic dyssynchrony index
KW  - Clinical outcome
KW  - Volumetric responders
N2  - Aim: The aim of this study was to compare the setting of interventricular (VV) delay by 3D echocardiography (3DE) using systolic dyssynchrony index (SDI) versus QRS width measurement in new cardiac resynchronization therapy (CRT) recipients. We observed the impact on the reduction of left ventricle volumes and increase in volumetric responders (defined as a = 15% reduction in left ventricular end-systolic volume (LVESv)) at the 6-month follow-up. Methods: We included 63 patients with recently implanted CRT in this open-label, randomized trial. Patients were randomized into two groups. VV delay was set by the QRS width in the group 1 (n 31) to obtain the narrowest QRS complex and by SDI in the group 2 (n 32) to achieve the lowest possible value. We evaluated LVESv, left ventricular ejection fraction (LVEF) by 3DE, before CRT implantation and at 6-month follow-up, in all patients. We also obtained clinical parameters and the level of NT-proBNP. Results: The second group showed only a trend toward greater reduction of LVESv (-33 +/- 55 ml vs. -48 +/- 43 ml; P 0.367), increase in LVEF (+ 7.3 +/- 10.9% vs. + 10.2 +/- 9.4%; P 0.210) and greater number of volumetric responders (14 vs. 18; P 0.612) compared with the group 1 at 6-month follow-up. There were also no significant differences in clinical outcomes and the level of NT-proBNP. Conclusion: Individual CRT optimization using SDI compared with QRS duration assessment did not reveal any significant differences in echocardiographic parameters and clinical outcomes at 6-month follow-up. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.
ER  -

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ a Petr VOJTISEK. Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation. \textit{cor et Vasa}. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč.~60, č.~4, s.~''E367''-''E376'', 10 s. ISSN~0010-8650. Dostupné z: https://dx.doi.org/10.1016/j.crvasa.2017.11.006.

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