Predictive value of the baseline electrocardiogram ST-segment
pattern in cardiogenic shock: Results from the CardShock Study

J 2018

Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study

JAVANAINEN, Tuija, Heli TOLPPANEN, Johan LASSUS, Markku S. NIEMINEN, Alessandro SIONIS et. al.

Základní údaje

Originální název

Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study

Autoři

JAVANAINEN, Tuija (246 Finsko, garant), Heli TOLPPANEN (246 Finsko), Johan LASSUS (246 Finsko), Markku S. NIEMINEN (246 Finsko), Alessandro SIONIS (724 Španělsko), Jindřich ŠPINAR (203 Česká republika, domácí), Jose SILVA-CARDOSO (620 Portugalsko), Matias LINDHOLM (208 Dánsko), Marek BANASZEWSKI (616 Polsko), Veli-Pekka HARJOLA (246 Finsko) a Raija JURKKO (246 Finsko)

Vydání

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, HOBOKEN, WILEY, 2018, 1082-720X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.235

Kód RIV

RIV/00216224:14110/18:00104203

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1111/anec.12561

UT WoS

000443676200010

Klíčová slova anglicky

acute coronary syndrome; acute heart failure; cardiogenic shock; electrocardiography; prognosis

Štítky

14110211, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 2. 2019 17:45, Soňa Böhmová

Anotace

V originále

BackgroundThe most common aetiology of cardiogenic shock (CS) is acute coronary syndrome (ACS), but even up to 20%-50% of CS is caused by other disorders. ST-segment deviations in the electrocardiogram (ECG) have been investigated in patients with ACS-related CS, but not in those with other CS aetiologies. We set out to explore the prevalence of different ST-segment patterns and their associations with the CS aetiology, clinical findings and 90-day mortality. MethodsWe analysed the baseline ECG of 196 patients who were included in a multinational prospective study of CS. The patients were divided into 3 groups: (a) ST-segment elevation (STE). (b) ST-segment depression (STDEP). (c) No ST-segment deviation or ST-segment impossible to analyse (NSTD). A subgroup analysis of the ACS patients was conducted. ResultsST-segment deviations were present in 80% of the patients: 52% had STE and 29% had STDEP. STE was associated with the ACS aetiology, but one-fourth of the STDEP patients had aetiology other than ACS. The overall 90-day mortality was 41%: in STE 47%, STDEP 36% and NSTD 33%. In the multivariate mortality analysis, only STE predicted mortality (HR 1.74, CI95 1.07-2.84). In the ACS subgroup, the patients were equally effectively revascularized, and no differences in the survival were noted between the study groups. ConclusionST-segment elevation is associated with the ACS aetiology and high mortality in the unselected CS population. If STE is not present, other aetiologies must be considered. When effectively revascularized, the prognosis is similar regardless of the ST-segment pattern in ACS-related CS.

Citovat

JAVANAINEN, Tuija, Heli TOLPPANEN, Johan LASSUS, Markku S. NIEMINEN, Alessandro SIONIS, Jindřich ŠPINAR, Jose SILVA-CARDOSO, Matias LINDHOLM, Marek BANASZEWSKI, Veli-Pekka HARJOLA a Raija JURKKO. Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY. HOBOKEN: WILEY, 2018, roč. 23, č. 5, s. 1-9. ISSN 1082-720X. Dostupné z: https://dx.doi.org/10.1111/anec.12561.

@article{1455636,
   author = {Javanainen, Tuija and Tolppanen, Heli and Lassus, Johan and Nieminen, Markku S. and Sionis, Alessandro and Špinar, Jindřich and SilvaandCardoso, Jose and Lindholm, Matias and Banaszewski, Marek and Harjola, VeliandPekka and Jurkko, Raija},
   article_location = {HOBOKEN},
   article_number = {5},
   doi = {http://dx.doi.org/10.1111/anec.12561},
   keywords = {acute coronary syndrome; acute heart failure; cardiogenic shock; electrocardiography; prognosis},
   language = {eng},
   issn = {1082-720X},
   journal = {ANNALS OF NONINVASIVE ELECTROCARDIOLOGY},
   title = {Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study},
   volume = {23},
   year = {2018}
}

TY  - JOUR
ID  - 1455636
AU  - Javanainen, Tuija - Tolppanen, Heli - Lassus, Johan - Nieminen, Markku S. - Sionis, Alessandro - Špinar, Jindřich - Silva-Cardoso, Jose - Lindholm, Matias - Banaszewski, Marek - Harjola, Veli-Pekka - Jurkko, Raija
PY  - 2018
TI  - Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study
JF  - ANNALS OF NONINVASIVE ELECTROCARDIOLOGY
VL  - 23
IS  - 5
SP  - 1-9
EP  - 1-9
PB  - WILEY
SN  - 1082720X
KW  - acute coronary syndrome
KW  - acute heart failure
KW  - cardiogenic shock
KW  - electrocardiography
KW  - prognosis
N2  - BackgroundThe most common aetiology of cardiogenic shock (CS) is acute coronary syndrome (ACS), but even up to 20%-50% of CS is caused by other disorders. ST-segment deviations in the electrocardiogram (ECG) have been investigated in patients with ACS-related CS, but not in those with other CS aetiologies. We set out to explore the prevalence of different ST-segment patterns and their associations with the CS aetiology, clinical findings and 90-day mortality. MethodsWe analysed the baseline ECG of 196 patients who were included in a multinational prospective study of CS. The patients were divided into 3 groups: (a) ST-segment elevation (STE). (b) ST-segment depression (STDEP). (c) No ST-segment deviation or ST-segment impossible to analyse (NSTD). A subgroup analysis of the ACS patients was conducted. ResultsST-segment deviations were present in 80% of the patients: 52% had STE and 29% had STDEP. STE was associated with the ACS aetiology, but one-fourth of the STDEP patients had aetiology other than ACS. The overall 90-day mortality was 41%: in STE 47%, STDEP 36% and NSTD 33%. In the multivariate mortality analysis, only STE predicted mortality (HR 1.74, CI95 1.07-2.84). In the ACS subgroup, the patients were equally effectively revascularized, and no differences in the survival were noted between the study groups. ConclusionST-segment elevation is associated with the ACS aetiology and high mortality in the unselected CS population. If STE is not present, other aetiologies must be considered. When effectively revascularized, the prognosis is similar regardless of the ST-segment pattern in ACS-related CS.
ER  -

JAVANAINEN, Tuija, Heli TOLPPANEN, Johan LASSUS, Markku S. NIEMINEN, Alessandro SIONIS, Jindřich ŠPINAR, Jose SILVA-CARDOSO, Matias LINDHOLM, Marek BANASZEWSKI, Veli-Pekka HARJOLA a Raija JURKKO. Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study. \textit{ANNALS OF NONINVASIVE ELECTROCARDIOLOGY}. HOBOKEN: WILEY, 2018, roč.~23, č.~5, s.~1-9. ISSN~1082-720X. Dostupné z: https://dx.doi.org/10.1111/anec.12561.

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