Další formáty:
BibTeX
LaTeX
RIS
@article{1456256,
author = {Gabbasov, Zufar and Kozlov, Sergey and Melnikov, Ivan and Byazrova, Svetlana and Saburova, Olga and Prokofieva, Lyudmila and Caprnda, Martin and Curilla, Eduard and Gaspar, Ludovit and Rodrigo, Luis and Kružliak, Peter and Smirnov, Vladimir},
article_location = {Thousand Oaks},
article_number = {8},
doi = {http://dx.doi.org/10.1177/1076029618771752},
keywords = {coronary artery disease; diabetes mellitus; drug-eluting stents; restenosis; CD45+platelet count; neutrophil to lymphocyte ratio},
language = {eng},
issn = {1076-0296},
journal = {Clinical and Applied Thrombosis-Hemostasis},
title = {Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease},
volume = {24},
year = {2018}
}
TY - JOUR
ID - 1456256
AU - Gabbasov, Zufar - Kozlov, Sergey - Melnikov, Ivan - Byazrova, Svetlana - Saburova, Olga - Prokofieva, Lyudmila - Caprnda, Martin - Curilla, Eduard - Gaspar, Ludovit - Rodrigo, Luis - Kružliak, Peter - Smirnov, Vladimir
PY - 2018
TI - Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease
JF - Clinical and Applied Thrombosis-Hemostasis
VL - 24
IS - 8
SP - 1308-1314
EP - 1308-1314
PB - Sage Publications Inc.
SN - 10760296
KW - coronary artery disease
KW - diabetes mellitus
KW - drug-eluting stents
KW - restenosis
KW - CD45+platelet count
KW - neutrophil to lymphocyte ratio
N2 - The purpose of the study was to assess whether the occurrence of restenosis is associated with CD45+ platelet count and neutrophil to lymphocyte ratio in patients with type 2 diabetes mellitus (DM) after drug-eluting stent (DES) implantation for stable coronary artery disease (CAD). The study comprised 126 patients, including 55 patients with type 2 DM and stable CAD who underwent elective coronary artery stenting with DES and follow-up angiography within 6 to 12 months. Blood samples were collected from each patient on the morning of the coronary angiography procedure. The variables related to in-stent restenosis were selected by logistic regression analysis. The logistic regression analysis showed that 2 inflammatory factors, CD45+ platelet count (odds ratio [OR] = 4.51, 95% confidence interval [CI]: 1.50-13.50, P = .007) and neutrophil to lymphocyte ratio (OR = 3.09, 95% CI: 1.05-9.10, P = .04), were significantly associated with the risk of in-stent restenosis after stenting with DES in patients with stable CAD and type 2 DM. A receiver operator characteristic curve analysis indicated that the area under the curve was 0.83% (0.05%; P < .001), which showed that the logistic model had good predictive accuracy (based on CD45+ platelet count and neutrophil to lymphocyte ratio) for the risk of in-stent restenosis development in DES in patients with CAD and type 2 DM. Two novel biomarkers of restenosis, CD45+ platelet count and neutrophil to lymphocyte ratio, may be effectively used to predict in-stent restenosis after DES implantation in patients with CAD and type 2 DM.
ER -
GABBASOV, Zufar, Sergey KOZLOV, Ivan MELNIKOV, Svetlana BYAZROVA, Olga SABUROVA, Lyudmila PROKOFIEVA, Martin CAPRNDA, Eduard CURILLA, Ludovit GASPAR, Luis RODRIGO, Peter KRUŽLIAK a Vladimir SMIRNOV. Novel Biomarkers for Coronary Restenosis Occurrence After Drug-Eluting Stent Implantation in Patients With Diabetes Having Stable Coronary Artery Disease. \textit{Clinical and Applied Thrombosis-Hemostasis}. Thousand Oaks: Sage Publications Inc., 2018, roč.~24, č.~8, s.~1308-1314. ISSN~1076-0296. Dostupné z: https://dx.doi.org/10.1177/1076029618771752.
|
