HEISSIGEROVÁ, Jarmila, David CALLANAN, Marc DE SMET, Sunil K. SRIVASTAVA, Michala KARKANOVÁ, Olga GARCIA-GARCIA and Sibel KADAYIFCILAR. Efficacy and Safety of Sarilumab for Noninfectious Uveitis of Posterior Segment: Outcomes From the Phase 2 SATURN Trial. Ophthalmology. 2019, p. 1549-4713. ISSN 0161-6420. Available from: https://dx.doi.org/10.1016/j.ophtha.2018.09.044.
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Basic information
Original name Efficacy and Safety of Sarilumab for Noninfectious Uveitis of Posterior Segment: Outcomes From the Phase 2 SATURN Trial
Name in Czech Účinnost a bezpečnost Sarilumabu u neinfekční zadní uveitidy: Výsledky 2. fáze studie SATURN
Authors HEISSIGEROVÁ, Jarmila, David CALLANAN, Marc DE SMET, Sunil K. SRIVASTAVA, Michala KARKANOVÁ, Olga GARCIA-GARCIA and Sibel KADAYIFCILAR.
Edition Ophthalmology, 2019, 0161-6420.
Other information
Original language English
Type of outcome Article in a journal
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 8.470
Doi http://dx.doi.org/10.1016/j.ophtha.2018.09.044
UT WoS 000459505400026
Keywords (in Czech) Sarilumab, zadní uveitidy, protilátka proti interleukin-6 receptoru
Keywords in English Sarilumab, rear uveitis, anti-interleukin-6 receptor antibody
Tags anti-interleukin-6 receptor antibody, Sarilumab
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 25/2/2019 11:15.
Abstract
To assess efficacy and safety of sarilumab, a human anti-interleukin-6 receptor antibody, for treatment of posterior segment noninfectious uveitis (NIU).Subcutaneous sarilumab may provide clinical benefits in the management of NIU of the posterior segment, especially in eyes with uveitic macular edema.
Abstract (in Czech)
Posoudit účinnost a bezpečnost sarilumabu, lidské protilátky proti receptoru interleukinu-6, pro léčbu neinfekční uveitidy zadního segmentu (NIU).Subkutánní sarilumab může poskytnout klinické přínosy při léčbě NIU zadního segmentu, zejména u očí s uveitickým makulárním edémem.
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