JANOUTOVA, J., P. AMBROZ, M. KOVALOVA, O. MACHACZKA, K. NEMCEK, A. ZATLOUKALOVA, E. MRAZKOVA, O. KOSTA, Alice HÁLOVÁ, Ladislav HOSÁK a Vladimír JANOUT. Epidemiology of mild cognitive impairment. Ceska a slovenska neurologie a neurochirurgie. Praha: Česká lékařská společnost J.E. Purkyně, 2018, roč. 81, č. 3, s. 284-289. ISSN 1210-7859. Dostupné z: https://dx.doi.org/10.14735/amcsnn2018284. |
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@article{1482215, author = {Janoutova, J. and Ambroz, P. and Kovalova, M. and Machaczka, O. and Nemcek, K. and Zatloukalova, A. and Mrazkova, E. and Kosta, O. and Hálová, Alice and Hosák, Ladislav and Janout, Vladimír}, article_location = {Praha}, article_number = {3}, doi = {http://dx.doi.org/10.14735/amcsnn2018284}, keywords = {mild cognitive impairment; dementia; epidemiology; risk factors}, language = {cze}, issn = {1210-7859}, journal = {Ceska a slovenska neurologie a neurochirurgie}, title = {Epidemiology of mild cognitive impairment}, url = {http://dx.doi.org/10.14735/amcsnn2018284}, volume = {81}, year = {2018} }
TY - JOUR ID - 1482215 AU - Janoutova, J. - Ambroz, P. - Kovalova, M. - Machaczka, O. - Nemcek, K. - Zatloukalova, A. - Mrazkova, E. - Kosta, O. - Hálová, Alice - Hosák, Ladislav - Janout, Vladimír PY - 2018 TI - Epidemiology of mild cognitive impairment JF - Ceska a slovenska neurologie a neurochirurgie VL - 81 IS - 3 SP - 284-289 EP - 284-289 PB - Česká lékařská společnost J.E. Purkyně SN - 12107859 KW - mild cognitive impairment KW - dementia KW - epidemiology KW - risk factors UR - http://dx.doi.org/10.14735/amcsnn2018284 N2 - Background: Mild cognitive impairment (MCI) is a transitional phase between cognitive changes in physiological aging and early dementia. The amnestic form of MCI is considered a precursor to Alzheimer's disease. The increasing number of elderly persons in the population is as sociated with an increase in the prevalence of chronic diseases including cognitive impairment and subsequent dementia. Aim: The aim of this work is to describe factors influencing the decrease of cognitive functions and development of MCI and subsequent dementia. Hypertension, hypercholesterolemia, diabetes mellitus and obesity are more frequent during middle age and contribute to the risk of dementia in older age through various cerebrovascular diseases and inflammatory/neurodegenerative mechanisms. At the same time, impaired cognitive functioning is associated with behavioral and psychosocial factors. The article provides an overview of potential vascular, behavioral and psychosocial risk factors for MCI and dementia. Conclusion: Knowledge of the risk factors for MCI and dementia will allow early prevention and effective therapy of these serious diseases. ER -
JANOUTOVA, J., P. AMBROZ, M. KOVALOVA, O. MACHACZKA, K. NEMCEK, A. ZATLOUKALOVA, E. MRAZKOVA, O. KOSTA, Alice HÁLOVÁ, Ladislav HOSÁK a Vladimír JANOUT. Epidemiology of mild cognitive impairment. \textit{Ceska a slovenska neurologie a neurochirurgie}. Praha: Česká lékařská společnost J.E. Purkyně, 2018, roč.~81, č.~3, s.~284-289. ISSN~1210-7859. Dostupné z: https://dx.doi.org/10.14735/amcsnn2018284.
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