Therapeutic potential of vitamin E and its derivatives in
traumatic brain injury-associated dementia

J 2018

Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia

DOBROVOLNÝ, Jan, Martin SMRČKA a Julie BIENERTOVÁ VAŠKŮ

Základní údaje

Originální název

Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia

Autoři

DOBROVOLNÝ, Jan (203 Česká republika), Martin SMRČKA (203 Česká republika) a Julie BIENERTOVÁ VAŠKŮ (203 Česká republika, garant, domácí)

Vydání

NEUROLOGICAL SCIENCES, New York, Springer, 2018, 1590-1874

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Itálie

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.484

Kód RIV

RIV/00216224:14110/18:00105139

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s10072-018-3398-y

UT WoS

000433091600002

Klíčová slova anglicky

Traumatic brain injury; Vitamin E; alpha-Tocopherol; Oxidative stress; Dementia; Lazaroids

Štítky

14110518, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 5. 2019 14:38, Soňa Böhmová

Anotace

V originále

Traumatic brain injury is one of the most common causes for intervention in neurosurgery. Apart from its acute consequence, it can represent a further burden on individuals as well as society by being associated with significant comorbidity-mainly earlyonset dementia. Oxidative stress is one of the crucial mechanisms conferring the damage to nervous tissue, and it is believed it could be, to some extent, influenced by dietary composition, largely by antioxidants contained in the diet. Under stressful conditions, cell-derived reactive oxygen species in the brain can induce the formation of lipid peroxides and the shifting of redox homeostasis. This review discusses the potential of vitamin E as a potent antioxidant and its derived molecules, including vitamin E-based lazaroids, in traumatic brain injury, summarizing the current state of knowledge of its role in TBI-associated dementia.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

LM2011028, projekt VaV

Název: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX Národní infrastruktura pro výzkum toxických látek v prostředí

Citovat

DOBROVOLNÝ, Jan, Martin SMRČKA a Julie BIENERTOVÁ VAŠKŮ. Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia. NEUROLOGICAL SCIENCES. New York: Springer, 2018, roč. 39, č. 6, s. 989-998. ISSN 1590-1874. Dostupné z: https://dx.doi.org/10.1007/s10072-018-3398-y.

@article{1482336,
   author = {Dobrovolný, Jan and Smrčka, Martin and Bienertová Vašků, Julie},
   article_location = {New York},
   article_number = {6},
   doi = {http://dx.doi.org/10.1007/s10072-018-3398-y},
   keywords = {Traumatic brain injury; Vitamin E; alpha-Tocopherol; Oxidative stress; Dementia; Lazaroids},
   language = {eng},
   issn = {1590-1874},
   journal = {NEUROLOGICAL SCIENCES},
   title = {Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia},
   url = {https://link.springer.com/article/10.1007%2Fs10072-018-3398-y},
   volume = {39},
   year = {2018}
}

TY  - JOUR
ID  - 1482336
AU  - Dobrovolný, Jan - Smrčka, Martin - Bienertová Vašků, Julie
PY  - 2018
TI  - Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia
JF  - NEUROLOGICAL SCIENCES
VL  - 39
IS  - 6
SP  - 989-998
EP  - 989-998
PB  - Springer
SN  - 15901874
KW  - Traumatic brain injury
KW  - Vitamin E
KW  - alpha-Tocopherol
KW  - Oxidative stress
KW  - Dementia
KW  - Lazaroids
UR  - https://link.springer.com/article/10.1007%2Fs10072-018-3398-y
L2  - https://link.springer.com/article/10.1007%2Fs10072-018-3398-y
N2  - Traumatic brain injury is one of the most common causes for intervention in neurosurgery. Apart from its acute consequence, it can represent a further burden on individuals as well as society by being associated with significant comorbidity-mainly earlyonset dementia. Oxidative stress is one of the crucial mechanisms conferring the damage to nervous tissue, and it is believed it could be, to some extent, influenced by dietary composition, largely by antioxidants contained in the diet. Under stressful conditions, cell-derived reactive oxygen species in the brain can induce the formation of lipid peroxides and the shifting of redox homeostasis. This review discusses the potential of vitamin E as a potent antioxidant and its derived molecules, including vitamin E-based lazaroids, in traumatic brain injury, summarizing the current state of knowledge of its role in TBI-associated dementia.
ER  -

DOBROVOLNÝ, Jan, Martin SMRČKA a Julie BIENERTOVÁ VAŠKŮ. Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia. \textit{NEUROLOGICAL SCIENCES}. New York: Springer, 2018, roč.~39, č.~6, s.~989-998. ISSN~1590-1874. Dostupné z: https://dx.doi.org/10.1007/s10072-018-3398-y.

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