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@proceedings{1482476,
author = {Řemínek, Roman and Schejbal, Jan and Glatz, Zdeněk},
booktitle = {15th International Interdisciplinary Meeting on Bioanalysis CECE 2018.},
keywords = {capillary electrophoresis, Alzheimer's disease, beta-secretase, inhibition, fluorescent detection, FRET},
language = {eng},
title = {Capillary Electrophoretic Method with Fluorescence Detection as a Promising Tool for Screening of Beta-Secretase Inhibitors},
url = {http://www.ce-ce.org/},
year = {2018}
}
TY - CONF
ID - 1482476
AU - Řemínek, Roman - Schejbal, Jan - Glatz, Zdeněk
PY - 2018
TI - Capillary Electrophoretic Method with Fluorescence Detection as a Promising Tool for Screening of Beta-Secretase Inhibitors
KW - capillary electrophoresis, Alzheimer's disease, beta-secretase, inhibition, fluorescent detection, FRET
UR - http://www.ce-ce.org/
N2 - Alzheimer’s disease (AD) represents the most common cause of dementia. According to amyloid cascade hypothesis, pathogenesis of the disease could be slowed down or even stopped by inhibition of beta-secretase (BACE). Capillary electrophoretic (CE) methods are regarded as a promising tool for enzyme assays. A CE method with fluorescence detection for screening of potential BACE inhibitors was therefore introduced.
ER -
ŘEMÍNEK, Roman, Jan SCHEJBAL a Zdeněk GLATZ. Capillary Electrophoretic Method with Fluorescence Detection as a Promising Tool for Screening of Beta-Secretase Inhibitors. In \textit{15th International Interdisciplinary Meeting on Bioanalysis CECE 2018.}. 2018.
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